CAJ | 학술논문

目的观察妊娠对大鼠正畸牙移动的影响。方法选取48只体重为（250±25）g的Wistar大鼠，并将其分为对照组（非妊娠期）与实验组（妊娠期）。大鼠的上颌中切牙分别用弹簧以30g的力推向远中，在第2d、第7d、第14d观察并记录两个上颌中切牙近中向的距离。随后再利用显微镜观察组织学切片记录破骨细胞的数量，最后对这些数据进行样本t检验。结果两组在第2d、第7d、第14d正畸牙移动的距离相比较没有明显的差异（P>0.05），但是两组的破骨细胞数目存在明显差异（P<0.05），实验（妊娠）组的破骨细胞数目显著降低。结论妊娠期大鼠正畸牙的移动呈轻度减缓，并无统计学意义，但牙体受压侧破骨细胞的变化却有显著的统计学差异。
목적관찰임신대대서정기아이동적영향。방법선취48지체중위（250±25）g적Wistar대서，병장기분위대조조（비임신기）여실험조（임신기）。대서적상합중절아분별용탄황이30g적력추향원중，재제2d、제7d、제14d관찰병기록량개상합중절아근중향적거리。수후재이용현미경관찰조직학절편기록파골세포적수량，최후대저사수거진행양본t검험。결과량조재제2d、제7d、제14d정기아이동적거리상비교몰유명현적차이（P>0.05），단시량조적파골세포수목존재명현차이（P<0.05），실험（임신）조적파골세포수목현저강저。결론임신기대서정기아적이동정경도감완，병무통계학의의，단아체수압측파골세포적변화각유현저적통계학차이。
Objective To explore the affection of pregnancy on rat orthodontic tooth movement. Methods 48 Wistar rats, weighing 250g (±25g), were selected and randomly divided into 2 groups:pregnancy group and non-pregnancy group;the maxillary central inci-sors of all the rats in both groups were pulled by spring with a power of 30g to the distal and the mesial distance between the two maxil-lary central incisors was measured and recorded on the 2nd, the 7th and the 14th day;microscopic observation was made to the histological slices and the number of osteoclast was counted;all the data received t test. Results There existed no obvious difference of the distance in orthodontic tooth movement on the 2nd, the 7th and the 14th day between the 2 groups (P>0.05) while the numbers of osteoclast in the 2 groups were quite different (P<0.05), the number of osteoclast in pregnancy group decreased obviously. Conclusions Rat orthodontic tooth movement in pregnancy is slightly alleviated without statistical significance;the change of osteoclast on the compressed side of the tooth is of great statistical difference.