CAJ | 학술논문

对氟吗啉的合成工艺进行了研究，以邻苯二酚为起始原料，通过醚化、付克酰基化、缩合反应制得目标化合物，总收率可达69．1％。目标产物及中间体的结构均经NMR、MS确证。改用低毒和高活性试剂使合成工艺步骤简单，操作安全，条件温和，收率较高，适合大规模制备。
대불마람적합성공예진행료연구，이린분이분위기시원료，통과미화、부극선기화、축합반응제득목표화합물，총수솔가체69．1％。목표산물급중간체적결구균경NMR、MS학증。개용저독화고활성시제사합성공예보취간단，조작안전，조건온화，수솔교고，괄합대규모제비。
Flumorph was synthesized from catechol via etherification, Friedel--Crafts acyltion reaction and condensation reaction. The overall yield could reach 69. 1%. The product and all intermediates were characterized and verified by NMR and MS. The method has high industrial value thanks to its low production cost, convenient steps, simplicity and high yield.