CAJ | 학술논문

目的：探讨超敏C反应蛋白（ hs-CRP）检查对小儿流感早期诊断的意义及奥司他韦的疗效。方法2013年1～5月份潍坊地区来我科就诊患儿（年龄3～14岁）共980例，行血常规和hs-CRP检查，同时做呼吸道病毒检测。对hs-CRP正常和呼吸道病毒检测阳性者分为两组，治疗组给予口服可威，对照组给予口服利巴韦林颗粒。结果900例显示hs-CRP正常，呼吸道病毒检测均为阳性；80例显示hs-CRP明显升高，呼吸道病毒检测均呈阴性。治疗组与对照组比较相同时间内体温恢复快。治疗组患儿体温下降时间以及伴随症状的消失时间较对照组明显缩短（ P＜0．05）。结论单纯hs-CRP检查即可作为流感病毒感染的早期参考指标，可指导临床早期用药，尽快控制病情。可威治疗小儿流感起效快，能显著缩短病程，减少并发症。
목적：탐토초민C반응단백（ hs-CRP）검사대소인류감조기진단적의의급오사타위적료효。방법2013년1～5월빈유방지구래아과취진환인（년령3～14세）공980례，행혈상규화hs-CRP검사，동시주호흡도병독검측。대hs-CRP정상화호흡도병독검측양성자분위량조，치료조급여구복가위，대조조급여구복리파위림과립。결과900례현시hs-CRP정상，호흡도병독검측균위양성；80례현시hs-CRP명현승고，호흡도병독검측균정음성。치료조여대조조비교상동시간내체온회복쾌。치료조환인체온하강시간이급반수증상적소실시간교대조조명현축단（ P＜0．05）。결론단순hs-CRP검사즉가작위류감병독감염적조기삼고지표，가지도림상조기용약，진쾌공제병정。가위치료소인류감기효쾌，능현저축단병정，감소병발증。
Objective To investigate the significance of high-sensitivity CRP ( hs-CRP) examination on ear-ly diagnosis of influenza and the efficacy of oseltamivir on influenza .Methods Nine hundred and eighty cases of chil-dren(aged 3~14 years) during the prevalence of influenza in weifang in 2013 from Jan.to May were enrolled,and they were given boood routine test and hs-CRP examination before treatment ,as well as respiratory virus detection .Subjects who got normal hs-CRP concentration and positive respiratory virus were divided equally into two groups:the Oseltamivir group and the Ribavirin group .Results Nine hundred cases of hs-CRP is normal,along with the positive respiratory vi-rus, while 80 cases hs-CRP show significantly elevated , along with negative respiratory virus .Subjects in Oseltamivir group showed the more temperature drops in the same time ,compared with those in control group .And the other is also accompanied by the disappearance of symptoms was significantly shorter than the control group .Conclusion Simple hs-CRP can be used as an early indicator of influenza virus infection .Results are reported quickly and clinical compliance rate is high .Early oseltamivir treatment can significantly reduce the fever symptoms ,shorten the course ,reduce pain and complications.