CAJ | 학술논문

目的：通过对萍乡市历年流感样病例的病毒核酸检测结果分析，了解当地流感疫情状况，分析当地流感发病趋势，为预防和控制流感流行提供科学论证凭据。方法萍乡市人民医院为国家流感样病例监测哨点医院，对符合流感样病例定义的病例收集相关信息，采集咽拭子标本，采用实时荧光逆转录聚合酶链反应法(real-time RT-PCR)对标本进行流感病毒核酸检测，并进行统计分析。结果萍乡市流感病毒核酸阳性率22.09%，其中2009年阳性率59.75%最高，之后呈下降趋势。新甲型H1N1流感病毒和乙型流感病毒阳性数接近，构成比分为33.74%和30.89%。新甲型H1N1共检出阳性166例，其中2009年9-12月检出阳性143例，2009年11月为最高峰，阳性率达到(75/143)52.45%，2010年以后有少量病例发现。乙型和季H3流感检出阳性数逐年增加。男、女流感核酸阳性检出率分别为23.19%(291/1255)和20.68%(201/972)。年龄分5个组统计分析，阳性率分别是37.25%、30.59%、19.40%、18.69%和13.00%。结论萍乡市流感病例核酸阳性以新甲型H1N1和乙型为主；季H3流感病例核酸阳性有所增加，且新甲型H1N1在2009年12月后得到有效控制，流感病毒易感染人群以学龄儿童和青少年为主，性别无差异。
목적：통과대평향시력년류감양병례적병독핵산검측결과분석，료해당지류감역정상황，분석당지류감발병추세，위예방화공제류감류행제공과학론증빙거。방법평향시인민의원위국가류감양병례감측초점의원，대부합류감양병례정의적병례수집상관신식，채집인식자표본，채용실시형광역전록취합매련반응법(real-time RT-PCR)대표본진행류감병독핵산검측，병진행통계분석。결과평향시류감병독핵산양성솔22.09%，기중2009년양성솔59.75%최고，지후정하강추세。신갑형H1N1류감병독화을형류감병독양성수접근，구성비분위33.74%화30.89%。신갑형H1N1공검출양성166례，기중2009년9-12월검출양성143례，2009년11월위최고봉，양성솔체도(75/143)52.45%，2010년이후유소량병례발현。을형화계H3류감검출양성수축년증가。남、녀류감핵산양성검출솔분별위23.19%(291/1255)화20.68%(201/972)。년령분5개조통계분석，양성솔분별시37.25%、30.59%、19.40%、18.69%화13.00%。결론평향시류감병례핵산양성이신갑형H1N1화을형위주；계H3류감병례핵산양성유소증가，차신갑형H1N1재2009년12월후득도유효공제，류감병독역감염인군이학령인동화청소년위주，성별무차이。
Objective To analyze the data from surveillance of influenza virus in Pingxiang city over the years and to explore the epidemic situation of influenza and incidence trend of influenza so as to provide scientific evidence for prevention and control of influenza credentials. Methods The relevant informations and throat swab specimens were collected from influenza-like pa-tients at the Pingxiang City People's Hospital,which is a national influenza surveillance hospital.The influenza virus nucleic acid was detected by using real-time RT-PCR method and statistical analysis was performed. Results In Pingxiang city, the positive rate of nucleic acid of influenza virus was 22.09%, but in 2009 the positive rate was 59.75%,which was the highest and then de-clining year by year. The positive rates of new influenza A (H1N1) virus and influenza B virus were close, which were 33.74%and 30.89%respectively. 166 samples were positive for new influenza A (H1N1), of which 143 samples were positive from September to December in 2009, the highest peak in November 2009, the positive rate was (75/143) 52.45%, a small number of cases was detected after 2010. The positive rate of B influenza and H3 influenza were increasing year by year. The positive rate in male were 23.19% (291/1255) and 20.68% (201/972) in female respectively. Conducting statistical analysis according to the age of five groups, the positive rate was 37.25%, 30.59%, 19.40%, 18.69% and 13.00%, respectively. Conclusions In Pingxiang influenza virus was mainly new influenza A (H1N1) and B influenza. The H3 influenza was increasing, but the new influenza A (H1N1) was effectively controlled after December 2009. The population susceptible to influenza virus was mainly school children and teenagers, there was no gender differences.