CAJ | 학술논문

目的：了解国内外替加环素作用于鲍曼不动杆菌的研究动态及热点内容。方法检索从建库至2014-03的Pubmed、Embase、Web of Science及CNKI数据库中替加环素对鲍曼不动杆菌作用相关文献；用Endnote7.0软件进行分类整理分析。结果纳入英文文献227篇，中文文献34篇；发表的文献类型以论著为主；文献的主要内容为替加环素对鲍曼不动杆菌作用相关的体外基础研究、动物实验、病例分析等；研究内容主要涉及耐药机制、体外药敏实验及联合用药等。结论替加环素作用于鲍曼不动杆菌的研究受到广泛关注，尤其是鲍曼不动杆菌对替加环素耐药机制的研究愈加深入。
목적：료해국내외체가배소작용우포만불동간균적연구동태급열점내용。방법검색종건고지2014-03적Pubmed、Embase、Web of Science급CNKI수거고중체가배소대포만불동간균작용상관문헌；용Endnote7.0연건진행분류정리분석。결과납입영문문헌227편，중문문헌34편；발표적문헌류형이론저위주；문헌적주요내용위체가배소대포만불동간균작용상관적체외기출연구、동물실험、병례분석등；연구내용주요섭급내약궤제、체외약민실험급연합용약등。결론체가배소작용우포만불동간균적연구수도엄범관주，우기시포만불동간균대체가배소내약궤제적연구유가심입。
Objective To analyze researches and hot issuses on tigecy-cline against Acinetobacter baumannii around the world.Methods Liter-atures were searched in Pubmed , Embase , Web of Science , and CNKI from the beginning to March , 2014.Endnote7.0 was used to sort out and summarize.Results A total of 227 English articles and 34 Chinese arti-cles were collected and the majority was characterized asoriginal article.Those articles were focused on the basic research of tigecycline against Acinetobacter baumannii in vitro, animal experiments and case analysis.Resistance mechanism , drug susceptibility test in vitro, and drug combi-nation were frequently involved.Conclusion The study on tigecycline against Acinetobacter baumannii increasingly has attracted global concern , especially the study on resistance mechanisms to tigecycline has gone fur-ther.