临床儿科杂志
臨床兒科雜誌
림상인과잡지
2014年
9期
895-897
,共3页
沈云琳(综述)%黄文彦(审校)
瀋雲琳(綜述)%黃文彥(審校)
침운림(종술)%황문언(심교)
急性肾损伤%肾小管重塑%肾小管上皮细胞
急性腎損傷%腎小管重塑%腎小管上皮細胞
급성신손상%신소관중소%신소관상피세포
acute kidney injury%renal tubule remodeling%renal tubular epithelial cells
急性肾损伤(AKI)是临床常见的危重症，病死率高。AKI时主要的受损细胞是肾小管上皮细胞。肾小管上皮细胞重塑在AKI发生发展、预后转归中起着至关重要的作用。肾小管重塑过程机制复杂，其确切调控机制尚不清楚，文章就AKI肾小管重塑调控机制进行综述。
急性腎損傷(AKI)是臨床常見的危重癥，病死率高。AKI時主要的受損細胞是腎小管上皮細胞。腎小管上皮細胞重塑在AKI髮生髮展、預後轉歸中起著至關重要的作用。腎小管重塑過程機製複雜，其確切調控機製尚不清楚，文章就AKI腎小管重塑調控機製進行綜述。
급성신손상(AKI)시림상상견적위중증，병사솔고。AKI시주요적수손세포시신소관상피세포。신소관상피세포중소재AKI발생발전、예후전귀중기착지관중요적작용。신소관중소과정궤제복잡，기학절조공궤제상불청초，문장취AKI신소관중소조공궤제진행종술。
Acute kidney injury (AKI) has emerged as a major public health problem that leads to decreased survival. Renal tubular epithelial cells are mainly damaged cells in AKI. Renal tubular epithelial cell remodeling plays a vital role in AKI. The regulatory mechanism of renal tubule remodeling is not yet clear. This review is written to address the renal tubule remodeling regulation mechanism of AKI.
