CAJ | 학술논문

目的观察分析经鼻持续气道正压通气(nCPAP)治疗对高血压合并中重度OSAHS患者血压及血清脂联素水平的影响.方法入选研究对象60例,诊断高血压合并中重度OSAHS明确,随机分为nCPAP治疗组与对照组.治疗组患者在治疗前后分别比较两组不同时间点血压及血清脂联素水平的变化,分析治疗对高血压合并中重度OSAHS患者血压及脂联素的影响.结果治疗后患者血压、血清脂联素水平均有所下降,晨起血压及脂联素下降较为显著.晨起血压差值与血清脂联素差值呈正相关.结论 nCPAP治疗可有效降低高血压合并中重度OSAHS患者血压及血清脂联素水平,且晨起血压的变化与脂联素的变化呈正相关.
목적 관찰분석경비지속기도정압통기(nCPAP)치료대고혈압합병중중도OSAHS환자혈압급혈청지련소수평적영향.방법 입선연구대상60례,진단고혈압합병중중도OSAHS명학,수궤분위nCPAP치료조여대조조.치료조환자재치료전후분별비교량조불동시간점혈압급혈청지련소수평적변화,분석치료대고혈압합병중중도OSAHS환자혈압급지련소적영향.결과 치료후환자혈압、혈청지련소수평균유소하강,신기혈압급지련소하강교위현저.신기혈압차치여혈청지련소차치정정상관.결론 nCPAP치료가유효강저고혈압합병중중도OSAHS환자혈압급혈청지련소수평,차신기혈압적변화여지련소적변화정정상관.
Objective To observe and analyze the effect of nasal continuous positive airway pressure (nCPAP) treatment on blood pressure and the level of serum Adiponectin in hypertension patients complicated with moderate or severe obstructive sleep apnea-hpopnea syndrom (OSAHS).Methods Sixty patients with hypertension complicated with moderate or sever OSAHS were recruited.All of the patients were divided into treatment group and control group.Treatment group received nCPAP treatment.After the treatment,the patients' blood pressure were measured and the levels of serum Adiponectin were tested before and after the treatment at the same point.Results NCPAP treatment lowered the levels of blood and serum Adiponectin,especially the morning point.There was significant positive correlation between the equation of Adiponectin and the equation of blood pressure in the morning.Conclusions NCPAP treatment can efficiently decrease the level of serum Adiponectin and the blood pressure in hypertension patients complicated with moderate or severe OSAHS.There was significant positive correlation between the change of Adiponectin and the change of blood pressure in morning after treatment.