CAJ | 학술논문

目的：评价布替萘芬治疗皮肤癣菌的疗效。方法选取有效皮肤癣菌病例189例，男108例，女81例，体癣43例，股癣38例、手足癣74例，花斑癣34例，年龄（38±25）岁，随机分为A、B两组；其中A组95例，男性61例，女性34例，体癣23例，股癣20例、手足癣37例，花斑癣15例，使用盐酸布替萘芬乳膏为治疗组；B组94例，男性47例，女性47例，体癣20例，股癣18例、手足癣37例，花斑癣19例，使用酮康唑乳膏为对照组。疗程4周。结果A组平均治愈率为100%，真菌菌检转阴率为93.7%；B组平均治愈率80.6%，真菌菌检转阴率为60.2%；停药8周后随访或检查，A组复发率为0，B组复发率为30.7%；说明布替萘芬疗效明显优于对照组（P＜0.05）。结论布替萘芬是治疗皮肤癣菌的有效药物，且优于酮康唑。
목적：평개포체내분치료피부선균적료효。방법선취유효피부선균병례189례，남108례，녀81례，체선43례，고선38례、수족선74례，화반선34례，년령（38±25）세，수궤분위A、B량조；기중A조95례，남성61례，녀성34례，체선23례，고선20례、수족선37례，화반선15례，사용염산포체내분유고위치료조；B조94례，남성47례，녀성47례，체선20례，고선18례、수족선37례，화반선19례，사용동강서유고위대조조。료정4주。결과A조평균치유솔위100%，진균균검전음솔위93.7%；B조평균치유솔80.6%，진균균검전음솔위60.2%；정약8주후수방혹검사，A조복발솔위0，B조복발솔위30.7%；설명포체내분료효명현우우대조조（P＜0.05）。결론포체내분시치료피부선균적유효약물，차우우동강서。
?Objective?Evaluation butenafine efficacy of treatment of dermatophytes. Methods Selected cases of 189 cases effectively dermatophytes, male 108 cases, female 81 cases, 43 cases of tinea corporis, tinea in 38 cases, 74 cases of hand, foot and ringworm, tinea versicolor, 34 patients aged 38±25a, were randomly divided into A, B two group;which A group of 95 cases, male 61, female 34 cases, 23 cases of tinea corporis, tinea in 20 cases, 37 cases of hand, foot and ringworm, tinea versicolor, 15 cases with butenafine hydrochloride cream for the treatment group;B group of 94 patients, male 47, female 47 cases, 20 cases of tinea corporis, tinea in 18 cases, 37 cases of hand, foot and ringworm, tinea versicolor in 19 cases, the use of ketoconazole cream as a control group, treatment 4wk. Results A group,the average cure rate was 100%, negative fungal strain was seized 93.7%, B group, the average cure rate was 80.6%, negative fungal strain was seized 60.2%;follow-up after drug withdrawal or check 8wk, A group the recurrence rate was 0, B group the recurrence rate was 34.0%;explained the butenafine the effect of was better than ketoconazole(P<0.05).?Conclusion Butenafine is an effective drug in the treatment of dermatophytes, and is superior to ketoconazole.