CAJ | 학술논문

目的探讨早发冠心病患者吸烟与冠状动脉病变的关系及其意义。方法选取经冠状动脉造影确诊的PCAD患者270例，其中男性158例、女性112例，采集患者吸烟史（吸烟年数、每日吸烟支数）、血脂水平（HDL- C、LDL- C、TG、TC），记录患者冠状动脉造影结果，同时进行相关性分析。结果吸烟指数与冠状动脉慢血流之间存在正相关（r=0.156,P＜0.05）；HDL- C与吸烟指数及Gensini积分均呈负相关（r=-0.136、-0.156，均P＜0.01）；吸烟指数与Gensini积分之间无线性相关关系（r=0.084，P＞0.05）。结论早发冠心病患者吸烟与HDL- C水平下降和冠状动脉慢血流现象相关。
목적탐토조발관심병환자흡연여관상동맥병변적관계급기의의。방법선취경관상동맥조영학진적PCAD환자270례，기중남성158례、녀성112례，채집환자흡연사（흡연년수、매일흡연지수）、혈지수평（HDL- C、LDL- C、TG、TC），기록환자관상동맥조영결과，동시진행상관성분석。결과흡연지수여관상동맥만혈류지간존재정상관（r=0.156,P＜0.05）；HDL- C여흡연지수급Gensini적분균정부상관（r=-0.136、-0.156，균P＜0.01）；흡연지수여Gensini적분지간무선성상관관계（r=0.084，P＞0.05）。결론조발관심병환자흡연여HDL- C수평하강화관상동맥만혈류현상상관。
Objective To assess association between smoking and coronary artery lesion in patients with premature coronary artery disease (CAD). Methods 270 patients (158 male, age<55y and 112 female, age<65y)with premature CAD determined by coronary angiography were enrol ed. Smoking amount, blood lipids and coronary artery angiograph-ic results were analyzed. Results There was a positive correlation between smoking index and coronary slow- flow phenomenon (r=0.156, P<0.05). HDL- C was negatively correlated with smoking index (r=- 0.136) and Gensini score (r=- 0.156)(al P<0.05) . There was no correlation between smoking index and Gensini score (r=0.084, P>0.05). Con-clusion Smoking is related to HDL- C decline and coronary slow flow phenomenon in patients with premature CAD. <br> Objective To assess association between smoking and coronary artery lesion in patients with premature coronary artery disease (CAD). Methods 270 patients (158 male, age<55y and 112 female, age<65y)with premature CAD determined by coronary angiography were enrol ed. Smoking amount, blood lipids and coronary artery angiograph-ic results were analyzed. Results There was a positive correlation between smoking index and coronary slow- flow phenomenon (r=0.156, P<0.05). HDL- C was negatively correlated with smoking index (r=- 0.136) and Gensini score (r=- 0.156)(al P<0.05) . There was no correlation between smoking index and Gensini score (r=0.084, P>0.05). Con-clusion Smoking is related to HDL- C decline and coronary slow flow phenomenon in patients with premature CAD.