东南大学学报（医学版）
東南大學學報（醫學版）
동남대학학보（의학판）
JOURNAL OF SOUTHEAST UNIVERSITY(MEDICAL SCIENCE EDITION)
2013年
6期
692-697
,共6页
REGMI Nikhil%孙子林%杨兵全
REGMI Nikhil%孫子林%楊兵全
REGMI Nikhil%손자림%양병전
糖尿病%运动%经皮氧分压%踝肱指数%周围动脉病变%定量振动阈值
糖尿病%運動%經皮氧分壓%踝肱指數%週圍動脈病變%定量振動閾值
당뇨병%운동%경피양분압%과굉지수%주위동맥병변%정량진동역치
diabetes mellitus%exercise%transcutaneous oxygen tension%ankle brachial index%peripheral arterial disease%quantitative sensory test
目的：研究运动对2型糖尿病患者下肢经皮氧分压（ tcpO2）的影响，以探索运动时的tcpO2动态变化对糖尿病患者循环障碍的诊断价值。方法：用踩踏功率自行车运动干预方法观察了12例2型糖尿病患者（24条下肢）以及3名正常成人（6条下肢）腓肠肌tcpO2的变化情况，同时检测静息状态下的踝肱比（ ABI）和定量振动阈值（ QST）。根据患者ABI水平将患者肢体分成＞0.9而≤1.3亚组、0.7～0.9亚组和＜0.7亚组3组，比较分析各组tcpO2变化情况。结果：所有糖尿病患者的tcpO2水平在运动过程中均出现下降趋势，而正常组则出现上升趋势。在静息状态下，tcpO2运动前后的变化值与ABI呈线性相关，但与QST并无线性关系。在ABI＞0.9而≤1.3亚组tcpO2在运动早期出现轻度升高，但随即下降到基础水平；在ABI为0.7～0.9亚组，tcpO2在运动初期即出现下降；在ABI＜0.7亚组则出现快速下降。结论：在运动中测量tcpO2水平有助于对糖尿病患者微循环储备功能的判断。
目的：研究運動對2型糖尿病患者下肢經皮氧分壓（ tcpO2）的影響，以探索運動時的tcpO2動態變化對糖尿病患者循環障礙的診斷價值。方法：用踩踏功率自行車運動榦預方法觀察瞭12例2型糖尿病患者（24條下肢）以及3名正常成人（6條下肢）腓腸肌tcpO2的變化情況，同時檢測靜息狀態下的踝肱比（ ABI）和定量振動閾值（ QST）。根據患者ABI水平將患者肢體分成＞0.9而≤1.3亞組、0.7～0.9亞組和＜0.7亞組3組，比較分析各組tcpO2變化情況。結果：所有糖尿病患者的tcpO2水平在運動過程中均齣現下降趨勢，而正常組則齣現上升趨勢。在靜息狀態下，tcpO2運動前後的變化值與ABI呈線性相關，但與QST併無線性關繫。在ABI＞0.9而≤1.3亞組tcpO2在運動早期齣現輕度升高，但隨即下降到基礎水平；在ABI為0.7～0.9亞組，tcpO2在運動初期即齣現下降；在ABI＜0.7亞組則齣現快速下降。結論：在運動中測量tcpO2水平有助于對糖尿病患者微循環儲備功能的判斷。
목적：연구운동대2형당뇨병환자하지경피양분압（ tcpO2）적영향，이탐색운동시적tcpO2동태변화대당뇨병환자순배장애적진단개치。방법：용채답공솔자행차운동간예방법관찰료12례2형당뇨병환자（24조하지）이급3명정상성인（6조하지）비장기tcpO2적변화정황，동시검측정식상태하적과굉비（ ABI）화정량진동역치（ QST）。근거환자ABI수평장환자지체분성＞0.9이≤1.3아조、0.7～0.9아조화＜0.7아조3조，비교분석각조tcpO2변화정황。결과：소유당뇨병환자적tcpO2수평재운동과정중균출현하강추세，이정상조칙출현상승추세。재정식상태하，tcpO2운동전후적변화치여ABI정선성상관，단여QST병무선성관계。재ABI＞0.9이≤1.3아조tcpO2재운동조기출현경도승고，단수즉하강도기출수평；재ABI위0.7～0.9아조，tcpO2재운동초기즉출현하강；재ABI＜0.7아조칙출현쾌속하강。결론：재운동중측량tcpO2수평유조우대당뇨병환자미순배저비공능적판단。
Objective:To study the influences of exercise on the trends of transcutaneous oxygen tension ( tcpO2 ) in lower limbs of patients with type 2 diabetes.Methods: Twelve diabetes ( test group ) and 3 healthy subjects ( control group) performed on the recumbent cycle ergometre (CE) with fixed seat.The tcpO2 was examined on the calf which represents local leg blood flow during exercise .Ankle brachial index (ABI) and quantitative sensory test ( QST) of the lower limbs were measured at resting state .According to the levels of subject's ABI, the diabetes were sub grouped into three scales (>0.9 and≤1.3, 0.7-0.9 and less 0.7).TcpO2 changes amongst the group were compared with different groups .Results:Pattern of post-exercise tcpO 2 change was unique for each sub group of diabetes in comparison to control group ( P<0.05 ) .Resting ABI level showed linear association with net tcpO 2 change ( r=0.493 , P<0.05 ) and displayed no association with QST level .Changes of tcpO 2 in time following exercise revealed unique pattern for different sub group; exercise increased the basal tcpO 2 level soon after the exercise and maintained even after end of exercise in control group .Diabetes with ABI>0.9 and≤1.3 group were marked with increase in tcpO 2 at the beginning and returned to initial level soon after the exercise .Exercise resulted in early decrease with compensatory increase in ABI 0.7-0.9 diabetes and declined sharply with no compensatory phase in ABI less 0.7 group.Conclusion: The tcpO2 tested during the exercise can reveal the reserve function of the circulation of the limbs in patients with type 2 diabetes .
