CAJ | 학술논문

目的：探讨中西医结合治疗Ⅱ型糖尿病的临床疗效及安全性。方法将80例Ⅱ型糖尿病患者用随机数字表分为治疗组42例，对照组38例。2组均予相同的基础治疗及相应的降糖、降血压、抗凝、改善心脑血液循环治疗。对照组加用盐酸吡格列酮胶囊30 mg，口服，日1次；治疗组加用中药水煎剂，日1剂。结果2组总有效率有非常显著性差异。治疗组降低体重指数、控制血糖，降低胆固醇、升高高密度脂蛋白疗效优于对照组，特别是治疗微量白蛋白尿明显优于对照组，有非常显著性意义。结论中西医结合治疗Ⅱ型糖尿病湿热困脾证疗效显著、安全、稳定。
목적：탐토중서의결합치료Ⅱ형당뇨병적림상료효급안전성。방법장80례Ⅱ형당뇨병환자용수궤수자표분위치료조42례，대조조38례。2조균여상동적기출치료급상응적강당、강혈압、항응、개선심뇌혈액순배치료。대조조가용염산필격렬동효낭30 mg，구복，일1차；치료조가용중약수전제，일1제。결과2조총유효솔유비상현저성차이。치료조강저체중지수、공제혈당，강저담고순、승고고밀도지단백료효우우대조조，특별시치료미량백단백뇨명현우우대조조，유비상현저성의의。결론중서의결합치료Ⅱ형당뇨병습열곤비증료효현저、안전、은정。
Objective To discuss the curative effect and safety of the therapy of integrated Chinese and Western medicine on type 2 diabetes. Methods The patients with type 2 diabetes (n=80) were randomly divided into treatment group (n=42) and control group (n=38) by using random digits table. The two groups were given the same basic therapy and corresponding treatments such as hypoglycemic therapy, hypotension therapy, anticoagulation therapy and improving cardio-cerebral blood circulation. Control group was given additionally oral Pioglitazone Hydrochloride Capsules (30 mg) once a day, and treatment group was given additionally Chinese medicinal decoction once a day. Results There was significant difference in the total effective rate between two groups. The curative effects of controlling blood sugar, decreasing body mass index and level of cholesterol, and increasing level of high-density lipoprotein were better in treatment group than those in control group, especially the effect of controlling microalbuminuria was greatly significant in treatment group. Conclusion The therapy of integrated Chinese and Western medicine has significant, safe and stable curative effect in the patients with type 2 diabetes (dampness-heat encumbering spleen syndrome).