北京中医药大学学报（中医临床版）
北京中醫藥大學學報（中醫臨床版）
북경중의약대학학보（중의림상판）
JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE(CLINICAL MEDICINE)
2013年
6期
20-22
,共3页
原发性血脂异常%证素%血脂指标%相关性%情志
原髮性血脂異常%證素%血脂指標%相關性%情誌
원발성혈지이상%증소%혈지지표%상관성%정지
primary dyslipidemia%syndrome factors%blood lipid indexes%correlation%emotion
目的：探讨原发性血脂异常患者情志证素的分布特点及与血脂指标的相关性。方法收集120例原发性血脂异常患者的一般资料、证素相关四诊信息、血脂指标。采用“证素辨证法”理论对证素进行诊断分级，采用SPSS 17.0统计软件进行分析。结果120例原发性血脂异常患者肝证素的诊断率最高，占78%。病位证素肝、肾、脾明显高于其他。病性证素湿、气滞、气虚、阴虚明显高于其他。高密度脂蛋白（HDL-C）、血脂载脂蛋白（ApoA1）均与肾、阴虚证素呈负相关，且随着证素程度加重，HDL-C、ApoA1有减少的趋势。结论原发性血脂异常的中医病位病机主要责之肝，其次为肾、脾。病性特点为虚实夹杂，虚多为阴虚、气虚，实多为湿和气滞。而肝气郁滞、肝肾阴虚考虑是原发性血脂异常中与中医情志相关的主要病机。HDL-C、ApoA1降低，定位在肾，定性为阴虚的可能性大。
目的：探討原髮性血脂異常患者情誌證素的分佈特點及與血脂指標的相關性。方法收集120例原髮性血脂異常患者的一般資料、證素相關四診信息、血脂指標。採用“證素辨證法”理論對證素進行診斷分級，採用SPSS 17.0統計軟件進行分析。結果120例原髮性血脂異常患者肝證素的診斷率最高，佔78%。病位證素肝、腎、脾明顯高于其他。病性證素濕、氣滯、氣虛、陰虛明顯高于其他。高密度脂蛋白（HDL-C）、血脂載脂蛋白（ApoA1）均與腎、陰虛證素呈負相關，且隨著證素程度加重，HDL-C、ApoA1有減少的趨勢。結論原髮性血脂異常的中醫病位病機主要責之肝，其次為腎、脾。病性特點為虛實夾雜，虛多為陰虛、氣虛，實多為濕和氣滯。而肝氣鬱滯、肝腎陰虛攷慮是原髮性血脂異常中與中醫情誌相關的主要病機。HDL-C、ApoA1降低，定位在腎，定性為陰虛的可能性大。
목적：탐토원발성혈지이상환자정지증소적분포특점급여혈지지표적상관성。방법수집120례원발성혈지이상환자적일반자료、증소상관사진신식、혈지지표。채용“증소변증법”이론대증소진행진단분급，채용SPSS 17.0통계연건진행분석。결과120례원발성혈지이상환자간증소적진단솔최고，점78%。병위증소간、신、비명현고우기타。병성증소습、기체、기허、음허명현고우기타。고밀도지단백（HDL-C）、혈지재지단백（ApoA1）균여신、음허증소정부상관，차수착증소정도가중，HDL-C、ApoA1유감소적추세。결론원발성혈지이상적중의병위병궤주요책지간，기차위신、비。병성특점위허실협잡，허다위음허、기허，실다위습화기체。이간기욱체、간신음허고필시원발성혈지이상중여중의정지상관적주요병궤。HDL-C、ApoA1강저，정위재신，정성위음허적가능성대。
Objective To discuss distribution characteristics of emotional syndrome factors in the patients with primary dyslipidemia and the correlations between these factors and blood lipid indexes. Methods The general information, information of TCM four examinations related to syndrome factors and blood lipid indexes were collected from the patients (n=120). The syndrome factors were determined and classified according to the theory of syndrome factors differentiation, and statistically analyzed by applying SPSS 17.0 software. Results Liver factor had the highest diagnostic rate (77.5%) in 120 patients. The occurrence frequencies of disease-location factors as liver, kidney and spleen were significantly higher than those of other disease-location factors. The occurrence frequencies of disease-nature factors as dampness, qi stagnation, qi deficiency and yin deficiency were significantly higher than those of other disease-nature factors. The levels of high density lipoprotein-cholesterol (HDL-C) and ApoA1 were negatively related to syndrome factors as kidney and yin deficiency, and the levels of HDL-C and ApoA1 had a descending trend with the aggravation of syndrome factors. Conclusion The major TCM pathogenesis of disease locations of primary dyslipidemia is liver followed by kidney and spleen. The characteristic of disease nature is a mixture of deficiency and excess. The deficiency syndromes are mainly yin deficiency and qi deficiency, while the excess syndromes are mainly dampness and qi stagnation. Liver qi stagnation and liver-kidney yin deficiency are the main pathogenesis of primary dyslipidemia related to TCM emotional theory. The reductions of HDL-C and ApoA1 levels are most probably related to kidney (location) and yin deficiency (nature).
