CAJ | 학술논문

目的：探讨在高场3T MRI上沉积于肺泡内的含有磷脂蛋白样物质的沉积物有无信号特点及其在肺泡蛋白沉积症诊断中的应用价值。方法：11例肺泡蛋白沉积症患者经纤维支气管镜肺活检病理确诊，先行肺部64层CT检查影像作为标准，再行3T MRI检查并与CT对照。结果：沉积在肺泡的含有蛋白样物质的沉积物呈稍长或等T1、稍长T2信号，无特殊信号特点，无强化。T2WI显示病变的分布、形态、数目、大小与CT一致。动态增强病灶内可见与肺动脉、肺静脉强化一致的增粗肺小动脉、肺小静脉，以肺小静脉增粗明显。结论：3T MRI T2WI容易发现沉积于肺泡内的含有蛋白样物质的沉积物，与CT一样能反映肺泡蛋白沉积症的形态学特征，但不能显示含有蛋白样物质的沉积物的信号特征，高场3T MRI可作为肺部疾病的补充检查方法。
목적：탐토재고장3T MRI상침적우폐포내적함유린지단백양물질적침적물유무신호특점급기재폐포단백침적증진단중적응용개치。방법：11례폐포단백침적증환자경섬유지기관경폐활검병리학진，선행폐부64층CT검사영상작위표준，재행3T MRI검사병여CT대조。결과：침적재폐포적함유단백양물질적침적물정초장혹등T1、초장T2신호，무특수신호특점，무강화。T2WI현시병변적분포、형태、수목、대소여CT일치。동태증강병조내가견여폐동맥、폐정맥강화일치적증조폐소동맥、폐소정맥，이폐소정맥증조명현。결론：3T MRI T2WI용역발현침적우폐포내적함유단백양물질적침적물，여CT일양능반영폐포단백침적증적형태학특정，단불능현시함유단백양물질적침적물적신호특정，고장3T MRI가작위폐부질병적보충검사방법。
Objective:To explore whether the phospholipidoproteinaceous material deposit within the alveoli by a high-ifeld 3T MRI has signal characters and its application for diagnosing pulmonary alveolar proteinosis.Methods:A total of 11 patients with pulmonary alveolar proteinosis previously diagnosed by ifberoptic bronchoscope lung biopsy underwent 64-slice helical CT scans and 3T MRI scans, and the CT scans and the MRI scans were compared. <br> Results:hTe phospholipidoproteinaceous material deposit within the alveoli presented longer or equal T1 relaxation time and longer T2 relaxation time, without characters of fatty or deposits of protein-like substance signals and enhancement. The distribution, form, number and size of the lesions at T2WI were almost the same as those at CT, the lesions were irregular in morphology, and there was a clear boundary between the lesions and the adjacent normal lung tissues. Dynamic contrast-enhanced MRI showed thickened pulmonary arteriolae and venulae in the lesions with more obviously thickened pulmonary venulae, which were in conformity with the pulmonary artery and venule enhancement. CT scan in 1 out of the 11 cases showed lesions in both lungs mainly consisted of stripe-shaped and reticular structures, and no obvious sign of pulmonary alveolar proteinosis residue was found. MRI scan detected alveolar proteinosis that failed to be shown by CT scan. <br> Conclusion:3T MRI T2WI can easily detect the lesions of long T2 signals formed by the lipoproteinaceous material deposit within the alveoli. In the lesions, geographic appearance was presented, and the crazy paving pattern was dimly visualized. MRI can relfect the morphological characters of PAP like CT and it is slightly better compared with CT in such aspects as evaluating the theraputic effect of lung lavage. As supplement to CT, high-field 3T MRI can serve as an important examination for lung diseases.