CAJ | 학술논문

目的：了解江苏省新报告HIV感染者/艾滋病患者（HIV/AIDS）新发感染状况。方法收集2011-2013年江苏省每年新报告的HIV/AIDS及其一般人口学资料、感染途径、样本来源等相关信息，并收集血清或血浆样本，进行BED检测，计算新发感染比例，研究新发感染的影响因素。结果同性传播的HIV/AIDS中新发感染比例最高（29.19%），其次是注射毒品（21.75%），异性传播最低（17.40%），不同感染途径间差异有统计学意义（P＜0.05）。新报告的HIV/AIDS中，与女性相比，男性更可能是新发感染（OR＝1.569，95%CI：1.168～2.107）；与＞35岁的相比，≤35岁的更可能是新发感染（OR＝1.556，95%CI：1.289～1.879）；与未婚相比，已婚有配偶的更可能是长期感染（OR＝0.789，95%CI：0.649～0.960）；与其他就诊者检测相比，通过检测咨询（OR＝2.278，95%CI：1.853～2.801）、专题调查（OR＝2.409，95%CI：1.860～3.120）及无偿献血人员检测（OR＝2.911，95%CI：2.118～4.001）更容易发现HIV新发感染者（P＜0.05）。结论江苏省新报告HIV/AIDS中MSM的新发感染比例最高；应加强主动监测，减少二代传播。
목적：료해강소성신보고HIV감염자/애자병환자（HIV/AIDS）신발감염상황。방법수집2011-2013년강소성매년신보고적HIV/AIDS급기일반인구학자료、감염도경、양본래원등상관신식，병수집혈청혹혈장양본，진행BED검측，계산신발감염비례，연구신발감염적영향인소。결과동성전파적HIV/AIDS중신발감염비례최고（29.19%），기차시주사독품（21.75%），이성전파최저（17.40%），불동감염도경간차이유통계학의의（P＜0.05）。신보고적HIV/AIDS중，여녀성상비，남성경가능시신발감염（OR＝1.569，95%CI：1.168～2.107）；여＞35세적상비，≤35세적경가능시신발감염（OR＝1.556，95%CI：1.289～1.879）；여미혼상비，이혼유배우적경가능시장기감염（OR＝0.789，95%CI：0.649～0.960）；여기타취진자검측상비，통과검측자순（OR＝2.278，95%CI：1.853～2.801）、전제조사（OR＝2.409，95%CI：1.860～3.120）급무상헌혈인원검측（OR＝2.911，95%CI：2.118～4.001）경용역발현HIV신발감염자（P＜0.05）。결론강소성신보고HIV/AIDS중MSM적신발감염비례최고；응가강주동감측，감소이대전파。
Objective To understand the status of recent infected and newly reported HIV cases in Jiangsu province. Methods Information including general demographic,mode of transmission and sample source of newly reported HIV infected cases was collected. Corresponding serum or plasma samples were collected and tested with BED-CEIA. Proportions of recent HIV infections among different populations were calculated,and associated factors of recent HIV infection calculated. Results Among cases infected through different channels as homosexual,heterosexual and needles sharing,the proportions of recent infections were 29.19%,17.40% and 21.75%, respectively. Statistically significant difference was seen between different populations(P<0.05). Compared with female cases,male cases were more likely to be recent infected(OR=1.569,95%CI:1.168-2.107). Compared with cases older than 35 years of age,the ones that younger than that age were more likely to be recently infected(OR=1.556,95%CI:1.289-1.879). Compared with cases who remained single,those married cases were more likely to be long-term infections(OR=0.789, 95%CI:0.649-0.960). Compared with patients identified by hospitals,the recent HIV infections were more likely to be found through voluntary counseling programs and testing(OR=2.278,95%CI:1.853-2.801),project-based surveillance programs(OR=2.409,95%CI:1.860- 3.120),and unpaid blood donation sites(OR=2.911,95%CI:2.118-4.001)(P<0.05). Conclusion Proportion of MSM ranked 1st in the newly reported HIV cases in Jiangsu province. Related HIV case-finding programs should be strengthened to reduce the secondary transmission.