CAJ | 학술논문

视网膜神经节细胞（ retinal ganglion cells ，RGCs）凋亡是青光眼、糖尿病视网膜病变、视神经炎等多种疾病过程中的一个重要环节。在这些疾病过程中，氧化应激参与诱导RGCs的凋亡。近年的实验研究发现抗氧化应激药物对RGCs有良好的保护作用。我们将近年来氧化应激诱导RGCs凋亡以及相关抗氧化应激药物的研究进展做一综述。
시망막신경절세포（ retinal ganglion cells ，RGCs）조망시청광안、당뇨병시망막병변、시신경염등다충질병과정중적일개중요배절。재저사질병과정중，양화응격삼여유도RGCs적조망。근년적실험연구발현항양화응격약물대RGCs유량호적보호작용。아문장근년래양화응격유도RGCs조망이급상관항양화응격약물적연구진전주일종술。
Apoptosis of retinal ganglion cells ( RGCs ) is an important step in the mechanism of a variety of diseases such as glaucoma, diabetic retinopathy, optic neuritis etc. In these diseases, oxidative stress induces the aopoptosis of RGCs.In recent years, many experimental studies have found that anti-oxidative stress drugs have a powerful protective efficacy in RGCs. This article reviewed the recent advances in the researches on oxidative stress-induced apoptosis of RGCs and related anti-oxidative stress drugs.