CAJ | 학술논문

目的：探讨内镜下醋酸联合靛胭脂染色对胃黏膜病变的临床诊断价值。方法选择高危患者356例，常规胃镜检查后行醋酸联合靛胭脂染色，分别观察并记录染色前后可疑病变的形态及色泽变化并进行活检。结果①染色检查的低级别上皮内瘤变、高级别上皮内瘤变、早期胃癌检出率均高于常规检查，正常及炎症检出率低于常规检查(P <0.05)。②常规检查检出的隆起型病灶占染色检查检出的44.9%，检出正确的平坦型病灶占染色检查检出的55.6%，检出凹陷型病灶占染色检查检出的63.0%；合计检出正确病灶率占染色检查检出的48.7%。结论内镜下醋酸联合靛胭脂染色可显著提高早期胃癌及高级别上皮内瘤变检出率。
목적：탐토내경하작산연합전연지염색대위점막병변적림상진단개치。방법선택고위환자356례，상규위경검사후행작산연합전연지염색，분별관찰병기록염색전후가의병변적형태급색택변화병진행활검。결과①염색검사적저급별상피내류변、고급별상피내류변、조기위암검출솔균고우상규검사，정상급염증검출솔저우상규검사(P <0.05)。②상규검사검출적륭기형병조점염색검사검출적44.9%，검출정학적평탄형병조점염색검사검출적55.6%，검출요함형병조점염색검사검출적63.0%；합계검출정학병조솔점염색검사검출적48.7%。결론내경하작산연합전연지염색가현저제고조기위암급고급별상피내류변검출솔。
Objective To evaluate the clinical value of acetic acid and indigo carmine staining in the diagnosis of gastric mucosal lesions. Methods Select 356 cases of high-risk patients, the gastric mucosal stained acetic acid and indigo carmine after conventional electronic endoscopy. The suspicious lesion morphology and color changes wer observed and recorded then biopsy before and after staining. Results The detection rates of low-grade intraepithelial neoplasia, high-grade intraepithelial neoplasia and early gastric cancer in staining group were hinger compared with conventional group(P <0.05). The detection rate of normal and inflammatory gastric mucosal in staining group were lower in staining group were hinger compared with conventional group, the difference was statistically significant(P <0.05). Polypoid lesions accounted for 44.9% of conventional examination detected in staining detected, flat-type lesions Accounted for 55.6% of conventional examination detected in staining detected. Depressed lesions accounted for 63.0%of conventional examination detected in staining detected. Total correct lesion detection rate accounted for 48.7% of conventional examination detected in staining detected. Conclusion The detection rates of early gastric cancer and high-grade intraepithelial neoplasia can be significantly improved by acetic acid and indigo carmine staining.