CAJ | 학술논문

目的：探讨连续性血液净化(CBP)救治重症艾滋病并急性肾衰竭的临床疗效。方法总结分析2011年6月至2013年6月我院收治28例重症艾滋病并急性肾衰竭患者的临床资料，在内科综合治疗基础上联合 CBP 治疗，观察 CBP 治疗前后临床症状改善情况和肾功能、血生化、血常规的变化。结果治疗后尿素氮、血肌酐、尿酸含量和 K+浓度较治疗前明显下降(P <0.05)；但治疗后血红蛋白、血小板、PH 值与治疗前比较没有统计学差异(P >0.05)。本组治疗72小时后，23例(82.1%)临床症状明显改善，肾功能恢复，5例（17.8%）死于原发病。结论 CBP 治疗重症艾滋病并急性肾衰竭患者疗效肯定，可以在临床上广泛应用，尤其是在没有设立艾滋病专门血液透析机的医院。
목적：탐토련속성혈액정화(CBP)구치중증애자병병급성신쇠갈적림상료효。방법총결분석2011년6월지2013년6월아원수치28례중증애자병병급성신쇠갈환자적림상자료，재내과종합치료기출상연합 CBP 치료，관찰 CBP 치료전후림상증상개선정황화신공능、혈생화、혈상규적변화。결과치료후뇨소담、혈기항、뇨산함량화 K+농도교치료전명현하강(P <0.05)；단치료후혈홍단백、혈소판、PH 치여치료전비교몰유통계학차이(P >0.05)。본조치료72소시후，23례(82.1%)림상증상명현개선，신공능회복，5례（17.8%）사우원발병。결론 CBP 치료중증애자병병급성신쇠갈환자료효긍정，가이재림상상엄범응용，우기시재몰유설립애자병전문혈액투석궤적의원。
Objective To investigate the clinical effect for continuous blood purification (CBP) in the treatment of severe AIDS combined with acute renal failure (ARF) . Methods Clinical data of 28 cases of severe AIDS patients with ARF in our hospital from June 2011 to June 2013 were summarized and analyzed. The improvement of clinical symptoms and the change of renal function, blood routine and biochemical indexes were measured before and after CBP treatment on the basis of comprehensive medical treatment. Results There were significantly decreased in content of blood urea nitrogen (BUN), serum creatinine (SCr) , uric acid and concentration of K+ (P <0.05) after CBP treatment; however, there were no significant differences in the levels of hemoglobin B(Hb), platelet(PLT) and PH value, as compared with those before treatment (P <0.05) .Twenty-three cases (82.1%) of clinical symptoms were particularly improved and renal function was recovered, five cases(17.8%)died of primary decease after 72h of treatment. Conclusion CBP is an effective method in treatment of severe AIDS accompanied with ARF. It can be widely used in clinical, particularly in the hospital in the absence of specialized hemodialysis machine for AIDS.