中国临床新医学
中國臨床新醫學
중국림상신의학
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
2014年
4期
296-299
,共4页
爱口含漱液%盐酸小檗碱%提取工艺%正交试验
愛口含漱液%鹽痠小檗堿%提取工藝%正交試驗
애구함수액%염산소벽감%제취공예%정교시험
Love mouth gargle liquid%Berberine hydrochloride%Extraction process%Orthogonal test
目的:优选爱口含漱液的提取工艺,保证制剂质量。方法以三因素(加水量、提取时间和提取次数)为考察因素,按三个指标(盐酸小檗碱含量、总多糖含量和浸膏率)采用综合评价方法考查爱口含漱液的最佳提取工艺。结果该制剂最佳提取工艺为加水量6倍,提取时间30 min,提取3次。结论优选最佳提取工艺方案可行,稳定性好,能有效保证制剂质量。
目的:優選愛口含漱液的提取工藝,保證製劑質量。方法以三因素(加水量、提取時間和提取次數)為攷察因素,按三箇指標(鹽痠小檗堿含量、總多糖含量和浸膏率)採用綜閤評價方法攷查愛口含漱液的最佳提取工藝。結果該製劑最佳提取工藝為加水量6倍,提取時間30 min,提取3次。結論優選最佳提取工藝方案可行,穩定性好,能有效保證製劑質量。
목적:우선애구함수액적제취공예,보증제제질량。방법이삼인소(가수량、제취시간화제취차수)위고찰인소,안삼개지표(염산소벽감함량、총다당함량화침고솔)채용종합평개방법고사애구함수액적최가제취공예。결과해제제최가제취공예위가수량6배,제취시간30 min,제취3차。결론우선최가제취공예방안가행,은정성호,능유효보증제제질량。
Objective To optimize the extraction process of love mouth gargle liquid , ensure the quality of preparation .Methods Taking three factors ( water volume , extracting time and extracting times ) as investigation fac-tors, with three indexes ( berberine hydrochloride content , total polysaccharide content and extract yield ) , the opti-mum extraction process of the love mouth gargle liquid was examined using the comprehensive evaluation method .Re-sults The optimum extraction process for preparation included adding 6 times amount of water ,extraction time of 30 minutes , 3 times of extraction .Conclusion The optimum extraction process is feasible , good stability ,can effective-ly guarantee the quality of preparation .