CAJ | 학술논문

　　目的：观察黛力新辅助奥美拉唑、莫沙必利治疗老年人胃食管反流病的临床疗效。方法：选取我院收治的129例老年胃食管反流病患者，随机分为观察组70例和对照组59例，对照组采用奥美拉唑联合莫沙必利治疗，观察组在对照组基础上加用黛力新。观察治疗后两组患者临床疗效以及反酸、烧心症状评分。结果：治疗后观察组总有效率为94.28%，对照组为61.02%，观察组总有效率明显高于对照组（P ＜0.05）；两组患者治疗后反酸和烧心等症状均有所改善，其中观察组4周后反酸症状评分明显低于对照组(P ＜0.05)；2周末烧心症状评分观察组优于对照组(P ＜0.05)。结论：黛力新辅助奥美拉唑、莫沙必利治疗老年人胃食管反流病临床疗效明显，对反酸、烧心等症状有明显改善作用，值得临床推广应用。
　　목적：관찰대력신보조오미랍서、막사필리치료노년인위식관반류병적림상료효。방법：선취아원수치적129례노년위식관반류병환자，수궤분위관찰조70례화대조조59례，대조조채용오미랍서연합막사필리치료，관찰조재대조조기출상가용대력신。관찰치료후량조환자림상료효이급반산、소심증상평분。결과：치료후관찰조총유효솔위94.28%，대조조위61.02%，관찰조총유효솔명현고우대조조（P ＜0.05）；량조환자치료후반산화소심등증상균유소개선，기중관찰조4주후반산증상평분명현저우대조조(P ＜0.05)；2주말소심증상평분관찰조우우대조조(P ＜0.05)。결론：대력신보조오미랍서、막사필리치료노년인위식관반류병림상료효명현，대반산、소심등증상유명현개선작용，치득림상추엄응용。
Objective: To explore the efficacy of deanxit combined with omeprazole and mosapride in treatment of elderly patients with gastroesophageal reflux disease. Methods:A total of 129 elderly patients with gastroesophageal reflux disease in our hospital,were randomly assigned to omeprazole,mosapride combined with deanxit(n=70) or omeprazole plus mosapride(n=59). the clinical efficacy and reflux, heartburn symptom score of the two groups were evaluated. Results: The total effective rate was higner in omeprazole,mosapride combined with deanxit (94.28%) than in omeprazole plus mosapride (61.02%). Reflux and heartburn and other symptoms in two groups were improved, and reflux symptoms score was significantly lower in omeprazole,mosapride combined with deanxit than in omeprazole plus mosapride(P< 0.05); Conclusion: improvement effect on reflux, heartburn and other symptoms is better in omeprazole,mosapride combined with deanxit than in omeprazole plus mosapride in senile patients with gastroesophageal reflux disease, and worthy of clinical application.