CAJ | 학술논문

目的：探究吸烟、饮酒与原发性肝癌发病年龄的相关性研究。方法：对549例原发性肝癌患者进行系统性分析，按照其是否吸烟、饮酒分为4组，即吸烟饮酒组、吸烟不饮酒组、饮酒不吸烟组以及既不吸烟也不饮酒组，分别用A、B、C、D代表各组，对比分析四组患者的平均发病年龄情况。结果：A组患者的平均发病年龄为（41.2±8.4）岁，B组患者的平均发病年龄为（47.6±7.9）岁，C组患者的平均发病年龄为（48.3±8.4）岁，D组患者的平均发病年龄为（57.4±6.9）岁，A组患者的发病年龄明显低于其余三组，且存在差异性（P<0.05），与D组患者的差异性更为明显（P<0.01），D组患者的发病年龄最晚。结论：饮酒是原发性肝癌密发病的高度危险因素，长时期的饮酒会使原发性肝癌的发病趋向年轻化，单独的吸烟对于原发性肝癌的发病年龄无明显影响，但吸烟及饮酒同时存在时，原发性肝癌的发病年龄明显年轻化。
목적：탐구흡연、음주여원발성간암발병년령적상관성연구。방법：대549례원발성간암환자진행계통성분석，안조기시부흡연、음주분위4조，즉흡연음주조、흡연불음주조、음주불흡연조이급기불흡연야불음주조，분별용A、B、C、D대표각조，대비분석사조환자적평균발병년령정황。결과：A조환자적평균발병년령위（41.2±8.4）세，B조환자적평균발병년령위（47.6±7.9）세，C조환자적평균발병년령위（48.3±8.4）세，D조환자적평균발병년령위（57.4±6.9）세，A조환자적발병년령명현저우기여삼조，차존재차이성（P<0.05），여D조환자적차이성경위명현（P<0.01），D조환자적발병년령최만。결론：음주시원발성간암밀발병적고도위험인소，장시기적음주회사원발성간암적발병추향년경화，단독적흡연대우원발성간암적발병년령무명현영향，단흡연급음주동시존재시，원발성간암적발병년령명현년경화。
Objective: To explore the smoking, drinking age correlation with primary liver cancer . Methods: 549 cases of primary liver cancer patients were systematicaly analyzed according to their smoking and drinking were divided into four groups, namely smoking and drinking group, the group of smokers without drinking , drinking and smoking group does neither smoking nor drinking group , respectively with a, B, C, D on behalf of the group, the average age of onset cases comparative analysis of the four groups of patients. Results: The mean age of onset for patients in group A (41.2 ± 8.4) years, the average age of onset group B patients was (47.6 ± 7.9) years, mean age of patients in group C was (48.3 ± 8.4) years old , D patients the average age was (57.4 ± 6.9) years of age , age of patients in group A was significantly lower than the other three groups , and there are differences (P <0.05), and D groups were more significant differences (P <0.01) , age of patients in group D at the latest . Conclusion: Drinking is a high risk factor in the pathogenesis of hepatocelular carcinoma dense , the incidence of primary liver cancer causes prolonged drinking of getting younger , the age of onset of smoking alone had no significant impact on primary liver cancer , but smoking and drinking At the same time the presence of the age of onset of primary liver cancer were significantly younger.