CAJ | 학술논문

目的：评估苦参联合动脉栓塞治疗原发性肝癌的临床效果和安全性。方法以我院2011年2月至2011年6月收治的第一次行介入治疗的73例原发性肝癌患者为研究对象，随机分A、B两组，分别以苦参联合碘油(A组)和碘油(B组)进行肝动脉栓塞术。观察和比较两组肿瘤缩小率、远期生存状况及术后不良反应的发生情况。结果栓塞治疗后A组的肿瘤缩小率、治疗间隔周期、生存率均高于对照组，而不良反应率的差异无统计学意义。结论苦参联合碘油栓塞治疗原发性肝癌可有效提高肿瘤缩小率及远期治疗效果，且不增加不良反应发生率。
목적：평고고삼연합동맥전새치료원발성간암적림상효과화안전성。방법이아원2011년2월지2011년6월수치적제일차행개입치료적73례원발성간암환자위연구대상，수궤분A、B량조，분별이고삼연합전유(A조)화전유(B조)진행간동맥전새술。관찰화비교량조종류축소솔、원기생존상황급술후불량반응적발생정황。결과전새치료후A조적종류축소솔、치료간격주기、생존솔균고우대조조，이불량반응솔적차이무통계학의의。결론고삼연합전유전새치료원발성간암가유효제고종류축소솔급원기치료효과，차불증가불량반응발생솔。
Objective To evaluate the clinical effects of Sophora combined with TAC for hepatocellular carcinoma patients. Methods Seventy-three patients with primary hepatic carcinoma were randomly divided into two groups. Sophora combined with lipiodol (group A) and iodized oil (group B) were used through hepatic artery. Adverse reactions were observed after the surgery, and the rate of tumor shrinkage and long-term survival were observed. Results After treatment, group A showed better results in aspects of interval period, rate of tumor shrinkage and survival rate than group B, while had no significant statistical difference in the rate of adverse reactions with group B. Conclusion Sophora combined with lipiodo for primary liver cancer does not increase the incidence of adverse reactions, but can effectively improve the rate of tumor shrinkage and long-term effects.