CAJ | 학술논문

手性拆分相比于传统的色谱分离，分离分析难度非常大．本文介结合近些年了科学研究的发展趋势总结了环糊精作为手性选择试剂在毛细管电泳手性分离中的应用，介绍了毛细管电泳的基本原理，环糊精及其衍生物是一种最常用的手性选择试剂，通过与被分析药物结合形成包合物，瞬时失去手性而实现手性拆分，并通过相关公式讨论了其拆分机理，并探讨了环糊精手性分离未来的发展方向，该分析方法极其经典，具有实用性．
수성탁분상비우전통적색보분리，분리분석난도비상대．본문개결합근사년료과학연구적발전추세총결료배호정작위수성선택시제재모세관전영수성분리중적응용，개소료모세관전영적기본원리，배호정급기연생물시일충최상용적수성선택시제，통과여피분석약물결합형성포합물，순시실거수성이실현수성탁분，병통과상관공식토론료기탁분궤리，병탐토료배호정수성분리미래적발전방향，해분석방법겁기경전，구유실용성．
Compared with conventional chromatographic separation, chiral separation and analysis is very diffcult. The basic principles of capillary electrophoresis was introduced in this article, the latest researches of chiral selectors cyclodextrin and its derivatives were specifically summarized. Cyclodextrin and analyte were binding to form inclusion complexes.