CAJ | 학술논문

建立人参糖肽注射液分子量分布测定方法。色谱柱为多糖专用凝胶柱OHpak SB-802 HQ （8mm ×300mm ），以0.9％氯化钠为流动相，流速0.5mL/min ，示差折光检测器。人参糖肽注射液重均分子量为900～1100u。本实验建立的多糖分子量测定方法具有简便、快速和重现性好的特点，为提高和完善该制剂的质量标准提供了依据，同时可作为指纹图谱从多糖肽分子量角度来控制该产品的内在质量。
건립인삼당태주사액분자량분포측정방법。색보주위다당전용응효주OHpak SB-802 HQ （8mm ×300mm ），이0.9％록화납위류동상，류속0.5mL/min ，시차절광검측기。인삼당태주사액중균분자량위900～1100u。본실험건립적다당분자량측정방법구유간편、쾌속화중현성호적특점，위제고화완선해제제적질량표준제공료의거，동시가작위지문도보종다당태분자량각도래공제해산품적내재질량。
To establish a quantitative method for molecular weight in Ginseng Glycopeptide injection solution .The determination was carried out using an OHpak SB-802 HQ(8mm × 300mm) .The mobile phase consisted of 0.9% sodium chloride solution at a flow rate of 0.5mL/min . The detection device was a refractive index detector .Molecular weight of Ginseng Glycopeptide Injection solution is 900-1 100u .The quantita-tive method was set up by polysaccharide molecular weight .The method is simple ,rapid and good reproducibility ,and can provide the basis for the improvement and optimization of the quality standard of Ginseng Glycopeptide Injection solution .It can be used as a fingerprint from the per-spective of polysaccharide peptide molecular weight to control the immanent quality of Ginseng Glycopeptide Injection solution .