CAJ | 학술논문

目的：观察不同压力高压氧（HBO）对颅脑外伤术后昏迷患者的早期疗效。方法按入组先后顺序随机将75例颅脑外伤术后昏迷患者分为对照组、0.20MPa高压氧组（HBO1组）和0.25MPa高压氧组（HBO2组），每组25例，比较三组患者在术后1周内和术后1月的格拉斯哥昏迷评分(GCS)，以及出院前的治愈显效率。结果（1）三组患者在术后1周内GCS评分无统计学差异（P>0.05），但治疗1月后GCS评分均提高（P<0.05）。（2）治疗后HBO1组和HBO2组GCS评分明显高于对照组，且HBO2组评分高于HBO1组（P<0.05）。（3） HBO1组和HBO2组的治愈显效率（76%和80%）明显高于对照组（48%）（P<0.05），但HBO1组和HBO2组之间无统计学差异（P>0.05）。结论早期两种压力的HBO治疗对颅脑外伤术后昏迷患者的恢复均有良好促进作用，其中0.25MPa压力的HBO对患者的促醒作用可能更优。
목적：관찰불동압력고압양（HBO）대로뇌외상술후혼미환자적조기료효。방법안입조선후순서수궤장75례로뇌외상술후혼미환자분위대조조、0.20MPa고압양조（HBO1조）화0.25MPa고압양조（HBO2조），매조25례，비교삼조환자재술후1주내화술후1월적격랍사가혼미평분(GCS)，이급출원전적치유현효솔。결과（1）삼조환자재술후1주내GCS평분무통계학차이（P>0.05），단치료1월후GCS평분균제고（P<0.05）。（2）치료후HBO1조화HBO2조GCS평분명현고우대조조，차HBO2조평분고우HBO1조（P<0.05）。（3） HBO1조화HBO2조적치유현효솔（76%화80%）명현고우대조조（48%）（P<0.05），단HBO1조화HBO2조지간무통계학차이（P>0.05）。결론조기량충압력적HBO치료대로뇌외상술후혼미환자적회복균유량호촉진작용，기중0.25MPa압력적HBO대환자적촉성작용가능경우。
Objective To observe the curative effect of hyperbaric oxygen (HBO) at different pressure as the early treatment on post-operative coma of patients with cerebral trauma. Methods 75 cases with cerebral trauma suffering from post-operative coma were randomly divided into 3 groups:HBO group 1 (at 0.20MPa),HBO group 2 (at 0.25MPa) and control group,25 in each;a comparative study was made to the Glasgow coma scores (GCS) of the patients in the 3 groups at 1 week and at 1 month after operation,as well as to the cured and obvious effective rate before discharge. Results There existed no statistical difference among the GCS at 1 week after operation of the patients in the 3 groups (P>0.05) while their scores all increased at 1 month after operation (P<0.05);the scores of HBO group 1 and HBO group 2 were both higher than that of control group after treatment,and the scores of HBO group 2 were higher than that of HBO group 1 (P<0.05);the obvious effective rates of HBO group 1 and HBO group 2 (76%and 80%) were significantly higher than that of control group (48%) (P<0.05) while no statistical difference was found between the rates of HBO group 1 and HBO group 2 (P>0.05). Conclusions Early treatment of HBO at two different pressures is of good effect on the recovery of patients with cerebral trau-ma suffering from post-operative coma,and HBO treatment at the pressure of 0.25MPa may be of more superior effect.