CAJ | 학술논문

目的：探究不同抗生素使用策略对胃癌术后感染情况的影响。方法选取行胃癌切除术患者150例作为临床研究资料，随机划分成传统策略组和改良策略组各75例。分别采用传统抗生素使用策略和改良策略干预手术的全过程，对比两组患者胃癌术后感染率和菌株耐药情况。结果改良策略组的胃癌术后感染率较传统策略组低（4.0％比14.7％）；菌株耐药比较传统策略组低（0比72.7％），差异均具有统计学意义（P＜0.05）。结论改良后的胃癌手术抗生素使用策略能有效降低术后感染几率，并防止菌株耐药的发生。
목적：탐구불동항생소사용책략대위암술후감염정황적영향。방법선취행위암절제술환자150례작위림상연구자료，수궤화분성전통책략조화개량책략조각75례。분별채용전통항생소사용책략화개량책략간예수술적전과정，대비량조환자위암술후감염솔화균주내약정황。결과개량책략조적위암술후감염솔교전통책략조저（4.0％비14.7％）；균주내약비교전통책략조저（0비72.7％），차이균구유통계학의의（P＜0.05）。결론개량후적위암수술항생소사용책략능유효강저술후감염궤솔，병방지균주내약적발생。
Objectives To investigate influences of different antibiotic application use strategies'on postoperative patients with gastric.Methods 150 cases of gastric cancer undertaken resection randomly divid-ed into traditional strategy group (75 cases) and improved strategy group (75 cases).Respectively Traditional antibiotic use strategy and improved strategy were adopted respectively within the whole process of surgery .Postoperative infection rates and bacterial strain's drug resistance situations wre compared between two.Results Postoperative infection rate and bacterial strain's drug resistance were lower in improved strategy groupthan in traditional strategy (4.0%vs 14.7%, 0 vs 72.7%), respectively, with significant difference (P<0.05).Conclusions Improved antibiotic use strategy can effectively reduce postoperative infection rate of gastric cancer patients , and can prevent occurrence of bacterial strain's drug resistance.