浙江化工
浙江化工
절강화공
ZHEJIANG CHEMICAL INDUSTRY
2013年
11期
21-23,38
,共4页
N,N-二异丙基乙二胺%Michael加成%Hofmann降解%催化剂
N,N-二異丙基乙二胺%Michael加成%Hofmann降解%催化劑
N,N-이이병기을이알%Michael가성%Hofmann강해%최화제
N,N-diisopropylethane-1,2-diamine%Michael addition%Hofmann degradation reaction%catalyst
以丙烯酰胺和二异丙胺为原料，创新性地采用三氟甲磺酸脯氨酸盐为催化剂，经过Michael加成反应合成N,N-二异丙氨基丙酰胺；再经过Hofmann降解反应得到N,N-二异丙基乙二胺，总收率54.0%，产品结构经过1H NMR、MS表征确证。
以丙烯酰胺和二異丙胺為原料，創新性地採用三氟甲磺痠脯氨痠鹽為催化劑，經過Michael加成反應閤成N,N-二異丙氨基丙酰胺；再經過Hofmann降解反應得到N,N-二異丙基乙二胺，總收率54.0%，產品結構經過1H NMR、MS錶徵確證。
이병희선알화이이병알위원료，창신성지채용삼불갑광산포안산염위최화제，경과Michael가성반응합성N,N-이이병안기병선알；재경과Hofmann강해반응득도N,N-이이병기을이알，총수솔54.0%，산품결구경과1H NMR、MS표정학증。
N,N-diisopropylethane-1,2-diamine was synthesized from diisopropylamine and acrylamide by Michael addition to give 3-(diisopropylamino)propanamide, which was subjected to Hofmann degradation to afford the target compound with an overall yield of 54.0%. The structures were confirmed by 1H NMR and MS.
