新医学
新醫學
신의학
NEW CHINESE MEDICINE
2013年
11期
770-774
,共5页
正常高值血压%危险因素
正常高值血壓%危險因素
정상고치혈압%위험인소
Prehypertension%Risk factor
目的：观察正常高值血压者与心血管危险因素之间的关系及其进展为高血压的危险因素。方法选取内蒙古自治区3年以上常住居民年龄20～59岁的正常高值血压伴心血管危险因素者共1112例，对所有研究对象收集年龄、身高、体质量、血压及心率等临床资料；采空腹血测定血脂、血糖、 hsCRP等生化指标。分别进行偏相关分析、多元逐步回归分析、 Logistic逐步回归分析。结果与结论①正常高值血压者收缩压与年龄、心率、甘油三酯、空腹血糖呈正相关；舒张压与年龄、心率、饮酒呈正相关；②年龄、心率、甘油三酯、家族史是收缩压的主要影响因素；年龄、性别、心率、 BMI、饮酒、家族史是舒张压的主要影响因素。③甘油三酯、 hsCRP 、饮酒、收缩压的增加是收缩期进展为高血压的主要危险因素， OR 值分别为1.967、1.377、2.197、1.995； BMI、hsCRP、饮酒、家族史及收缩压、舒张压的增加是舒张期进展为高血压的主要危险因素， OR值分别为1.516、1.847、0.234、2.908、1.749、1.600。
目的：觀察正常高值血壓者與心血管危險因素之間的關繫及其進展為高血壓的危險因素。方法選取內矇古自治區3年以上常住居民年齡20～59歲的正常高值血壓伴心血管危險因素者共1112例，對所有研究對象收集年齡、身高、體質量、血壓及心率等臨床資料；採空腹血測定血脂、血糖、 hsCRP等生化指標。分彆進行偏相關分析、多元逐步迴歸分析、 Logistic逐步迴歸分析。結果與結論①正常高值血壓者收縮壓與年齡、心率、甘油三酯、空腹血糖呈正相關；舒張壓與年齡、心率、飲酒呈正相關；②年齡、心率、甘油三酯、傢族史是收縮壓的主要影響因素；年齡、性彆、心率、 BMI、飲酒、傢族史是舒張壓的主要影響因素。③甘油三酯、 hsCRP 、飲酒、收縮壓的增加是收縮期進展為高血壓的主要危險因素， OR 值分彆為1.967、1.377、2.197、1.995； BMI、hsCRP、飲酒、傢族史及收縮壓、舒張壓的增加是舒張期進展為高血壓的主要危險因素， OR值分彆為1.516、1.847、0.234、2.908、1.749、1.600。
목적：관찰정상고치혈압자여심혈관위험인소지간적관계급기진전위고혈압적위험인소。방법선취내몽고자치구3년이상상주거민년령20～59세적정상고치혈압반심혈관위험인소자공1112례，대소유연구대상수집년령、신고、체질량、혈압급심솔등림상자료；채공복혈측정혈지、혈당、 hsCRP등생화지표。분별진행편상관분석、다원축보회귀분석、 Logistic축보회귀분석。결과여결론①정상고치혈압자수축압여년령、심솔、감유삼지、공복혈당정정상관；서장압여년령、심솔、음주정정상관；②년령、심솔、감유삼지、가족사시수축압적주요영향인소；년령、성별、심솔、 BMI、음주、가족사시서장압적주요영향인소。③감유삼지、 hsCRP 、음주、수축압적증가시수축기진전위고혈압적주요위험인소， OR 치분별위1.967、1.377、2.197、1.995； BMI、hsCRP、음주、가족사급수축압、서장압적증가시서장기진전위고혈압적주요위험인소， OR치분별위1.516、1.847、0.234、2.908、1.749、1.600。
Objective To observe the correlation between the prehypertension and cardiovascular risk factors and the risk factors of prehypertension developing into hypertension.Methods To choose 1 112 prehyertensive participants as subjects , who are accompanied by a high risk of cardiovascular disease , aged from 20 to 59 and have lived in Inner Mogonlia for at least three years.To collect such cilinical materials as age, height, weight, blood pressure and rhythm of the subjects.To collect fasting blood and measure its bio-chemical markers such as blood lipids and blood glucose , etc.Partial correlation analysis , multiple regression analysis and logistic regression analysis were applied , respectively.Results and conclusions ①Systolic blood pressure (SBP) is positively correlated with age, rhythm, triglyceride (TG) and fasting plasma glucose ( FPG);Diastolic blood pressure ( DBP) is positively correlated with age , rhythm and drinking.②The results show that major influence factors on SBP are age , rhythm, TG, family history.The major influence factors on DBP are age, gender, rhythm, BMI, drinking, family history.③With systolic and diastolic pressure of the subjects who develop into hypertention patients as virables , systolic pressure, diastolic pressure, gender, age, weight, BMI, waistline, TG, totalcholesterol (TC), HDL-C, LDL-C, FPG, hsCRP, smoking, drinking, fam-ily history as independent virable , Logistic stepwise regression analysis is performed , finding TC, hsCRP, smoking , drinking , family history are main risk factors for the development of hypertention.OR value is 1.967, 1.377, 2.197 and 1.995 respectively.BMI, hsCRP, drinking, family history, and the rising of systol-ic and diastolic pressure of the subjects are the risk factors of hypertention.OR value is 1.516, 1.814, 0.234, 2.908, 1.749, and 1.600, respectively.
