昆明医科大学学报
昆明醫科大學學報
곤명의과대학학보
Journal of Kunming Medical University
2013年
11期
93-96
,共4页
体外受精- 胚胎移植%雌二醇%黄体期%妊娠率
體外受精- 胚胎移植%雌二醇%黃體期%妊娠率
체외수정- 배태이식%자이순%황체기%임신솔
IVF-ET%Estradiol%Luteal phase%Pregnancy rate
目的:探讨胚胎移植后黄体期不同剂量戊酸雌二醇对体外受精-胚胎移植(IVF-ET)妊娠结局的影响.方法选取2011年2月至2012年10月在昆明医科大学第二附属医院生殖医学科接受IVF-ET的患者362例,随机分为3组,用标准长方案进行控制性超促排卵,均自取卵日后行黄体酮肌注60 mg/d.A组为对照组,112例,不加用戊酸雌二醇;B组为实验组1,122例,在移植后加用戊酸雌二醇4 mg/d;C组为实验组2,128例在移植后加用戊酸雌二醇6 mg/d;比较各组妊娠结局.结果 A组和B组的胚胎种植率和妊娠率差异无统计学意义(>0.05);B组和C组的胚胎种植率和妊娠率差异无统计学意义(>0.05);A组和C组的胚胎种植率和妊娠率差异有统计学意义(<0.05).结论6 mg/d补戊酸雌二醇用于黄体支持有可能提高IVF后的种植率和妊娠率.
目的:探討胚胎移植後黃體期不同劑量戊痠雌二醇對體外受精-胚胎移植(IVF-ET)妊娠結跼的影響.方法選取2011年2月至2012年10月在昆明醫科大學第二附屬醫院生殖醫學科接受IVF-ET的患者362例,隨機分為3組,用標準長方案進行控製性超促排卵,均自取卵日後行黃體酮肌註60 mg/d.A組為對照組,112例,不加用戊痠雌二醇;B組為實驗組1,122例,在移植後加用戊痠雌二醇4 mg/d;C組為實驗組2,128例在移植後加用戊痠雌二醇6 mg/d;比較各組妊娠結跼.結果 A組和B組的胚胎種植率和妊娠率差異無統計學意義(>0.05);B組和C組的胚胎種植率和妊娠率差異無統計學意義(>0.05);A組和C組的胚胎種植率和妊娠率差異有統計學意義(<0.05).結論6 mg/d補戊痠雌二醇用于黃體支持有可能提高IVF後的種植率和妊娠率.
목적:탐토배태이식후황체기불동제량무산자이순대체외수정-배태이식(IVF-ET)임신결국적영향.방법선취2011년2월지2012년10월재곤명의과대학제이부속의원생식의학과접수IVF-ET적환자362례,수궤분위3조,용표준장방안진행공제성초촉배란,균자취란일후행황체동기주60 mg/d.A조위대조조,112례,불가용무산자이순;B조위실험조1,122례,재이식후가용무산자이순4 mg/d;C조위실험조2,128례재이식후가용무산자이순6 mg/d;비교각조임신결국.결과 A조화B조적배태충식솔화임신솔차이무통계학의의(>0.05);B조화C조적배태충식솔화임신솔차이무통계학의의(>0.05);A조화C조적배태충식솔화임신솔차이유통계학의의(<0.05).결론6 mg/d보무산자이순용우황체지지유가능제고IVF후적충식솔화임신솔.
Objective To evaluate the influence of pregnancy outcomes with different dosage of estradiol valerate in addition to progesterone for luteal supplementation in IVF-ET cycles. Methods From February 2011 to October 2012, 362 patients undergoing IVF-ET in the second affiliated hospital of Kunming Medical University were selected. The patients were randomly assigned into three groups. Since oocyte retrieval, all of them were injected luteal supplementation with progesterone in oil 60 mg/d, im. Group A as control group (112 cases) did not add with pentanoic acid estradiol;Group B for the experimental group (122 cases), added pentanoic acid estradiol 4 mg/d after embryo transfer;Group C for the experimental group (128 cases) added pentanoic acid estradiol 6 mg/d after embryo transfer. Finally the pregnancy outcome and implantation rate were compared for each group. Results There were no significant differences between group A and group B, group B and group C in the rate of embryos grow and pregnancy rate ( >0.05) . The embryo planting rate and pregnancy rate have significant difference between Group A and group C ( < 0.05) . Conclusion 6 mg/d fill estradiol valerate for luteal supplementation may improve implantation rate and pregnancy rate after IVF.