CAJ | 학술논문

目的：了解儿童医院住院患儿抗菌药物的使用情况，为儿童合理用药提供参考．方法根据某儿童医院住院患者抗菌药物使用情况调查表，采用回顾性调查法随机抽取2012年7月至12月住院患儿病历180份对抗菌药物的使用率、品种选择、用药频次、单次用药剂量、联合用药、预防用药时间、用药疗程等情况进行统计分析．结果180份病历中使用抗菌药物的为110例（61.1%），使用抗菌药物的病历中抗菌药物联合使用为55例（50%），使用频率最高的是头孢菌素类，其次是β-内酰胺+酶抑制剂复合制剂.病历中出现用药频次不当的为12例（10.9%），单次剂量不当的为7例（6.4%），用药疗程不当的为9例（8.2%）.结论某儿童医院住院患儿抗菌药物的使用基本合理，但还存在品种选择不当、无指征使用、用法用量不当、疗程过长、联用不合理的情况，因此需加强抗菌药物的使用管理，提高抗菌药物临床合理应用水平．
목적：료해인동의원주원환인항균약물적사용정황，위인동합리용약제공삼고．방법근거모인동의원주원환자항균약물사용정황조사표，채용회고성조사법수궤추취2012년7월지12월주원환인병력180빈대항균약물적사용솔、품충선택、용약빈차、단차용약제량、연합용약、예방용약시간、용약료정등정황진행통계분석．결과180빈병력중사용항균약물적위110례（61.1%），사용항균약물적병력중항균약물연합사용위55례（50%），사용빈솔최고적시두포균소류，기차시β-내선알+매억제제복합제제.병력중출현용약빈차불당적위12례（10.9%），단차제량불당적위7례（6.4%），용약료정불당적위9례（8.2%）.결론모인동의원주원환인항균약물적사용기본합리，단환존재품충선택불당、무지정사용、용법용량불당、료정과장、련용불합리적정황，인차수가강항균약물적사용관리，제고항균약물림상합리응용수평．
Objective To realize the utilization of antibacterial drugs in pediatric inpatients in Children's Hospital for clinical reference of rational use of drugs. Methods By a retrospective study, 180 cases in pediatric inpatients were randomly sampled in Children's Hospital from July to December 2012, and were analyzed in utility rate, antibiotics varieties, administrational frequency,single dose,combination use,prophylaxis time,courses of drug use,etc. Results The use of antibacterial drugs in pediatric inpatients was 110 cases (61.1%) and used in combination was 55 cases (50%) . Leading the list in terms of DDDs was cephalosporins,followed byβ-lactam and its enzyme inhibitor complex preparations. The improper medications frequency was 12 cases (10.9%), irrational single dose was 7 cases (6.4%), and irrational course of treatment was 9 cases (8.2%) . Conclusion The utilization of antibacterial drugs in Children's Hospital is basically rational, but there still exist some irrational drug uses,such as antibiotics varieties,no indication, irrational dosage,long duration and irrational combination. So, it is necessary to enhance the administration of antibiotics use and improve the level of clinical reasonable application of antibiotics.