CAJ | 학술논문

目的：探讨超敏C反应蛋白（hs-CRP）在儿科感染性疾病中的诊断作用．方法采用BNProSpec全自动蛋白分析仪分别检测246例细菌性感染患儿（细菌感染组）、132例病毒性感染患儿（病毒感染组）及72例健康儿童（正常对照组）的血清hs-CRP含量．结果细菌感染组患儿血清hs-CRP的水平为（57.2±19.5） mg/L；病毒感染组患儿血清hs-CRP水平为（4.6±3.2） mg/L；正常对照组儿童血清hs-CRP的水平为（1.7±0.4） mg/L．hs-CRP在细菌感染患儿中的含量明显高于另外2组差异有统计学意义（＜0.05）．结论提示血清hs-CRP的检测在儿科感染性疾病的诊断、治疗及预后中具有较大的应用价值.
목적：탐토초민C반응단백（hs-CRP）재인과감염성질병중적진단작용．방법채용BNProSpec전자동단백분석의분별검측246례세균성감염환인（세균감염조）、132례병독성감염환인（병독감염조）급72례건강인동（정상대조조）적혈청hs-CRP함량．결과세균감염조환인혈청hs-CRP적수평위（57.2±19.5） mg/L；병독감염조환인혈청hs-CRP수평위（4.6±3.2） mg/L；정상대조조인동혈청hs-CRP적수평위（1.7±0.4） mg/L．hs-CRP재세균감염환인중적함량명현고우령외2조차이유통계학의의（＜0.05）．결론제시혈청hs-CRP적검측재인과감염성질병적진단、치료급예후중구유교대적응용개치.
Objective Explore the diagnostic effect of high-sensitivity C-reactive protein (hs-CRP) in pediatric infectious diseases. Methods The BNProSpec automatic protein analyzer was used to detect the serum hs-CRP levels of children including 246 cases of bacterial infection, 132 cases of virus infection and 72 cases of healthy children (control group) . Results The serum hs-CRP levels were 57.2±19.5 mg/L,4.6±3.2 mg/L and 1.7 ±0.4mg/L in children of the bacterial infection, virus infection and normal control group, respectively. Conclusion The serum levels of hs-CRP in children with bacterial infection were significantly higher than those in other two groups,and the difference was significant ( <0.05) . The results suggested that serum hs-CRP testing has great application value in the diagnosis of pediatric infectious diseases, treatment and prognosis.