CAJ | 학술논문

目的：通过1例经克拉屈滨治疗的复发毛细胞白血病的病例分析，进一步了解毛细胞白血病的治疗策略和方法。方法观察2012年4月我院收治的1例经克拉屈滨治疗的毛细胞白血病复发患者的治疗过程，分析毛细胞白血病的临床特点、治疗方法、治疗效果及不良反应，并复习有关文献。结果此例患者经1个疗程克拉屈滨治疗，3个月后达到部分缓解，随访5个月持续部分缓解。结论克拉屈滨是治疗毛细胞白血病的有效方法，不良反应小，耐受性好，适合在中国毛细胞白血病患者中应用。
목적：통과1례경극랍굴빈치료적복발모세포백혈병적병례분석，진일보료해모세포백혈병적치료책략화방법。방법관찰2012년4월아원수치적1례경극랍굴빈치료적모세포백혈병복발환자적치료과정，분석모세포백혈병적림상특점、치료방법、치료효과급불량반응，병복습유관문헌。결과차례환자경1개료정극랍굴빈치료，3개월후체도부분완해，수방5개월지속부분완해。결론극랍굴빈시치료모세포백혈병적유효방법，불량반응소，내수성호，괄합재중국모세포백혈병환자중응용。
Objective To study the treatment strategies and methods of hairy cell leukemia (HCL) by analyzing 1 case of relapsed HCL after treated with cladribine.Methods The clinical features, treatment methods and their effect, and adverse reactions of 1 case of relapsed HCL admitted to our hospital in April 2012 and treated with cladribine were analyzed with the related literature reviewed. Results The symptoms of the patient were partially alleviated 3 months after treated with cladribine. The patient was followed up for 5 months during which the symptoms were continuously and partially alleviated.Conclusion Cladribine is effective for HCL with few adverse reactions and good tolerance, and can thus be used in treatment of Chinese HCL patients.