CAJ | 학술논문

目的：分析气管镜介入相关诊疗并发大出血的危险因素。方法选择2011年12月-2012年12月解放军总医院呼吸科介入肺脏病中心经气管镜诊治的患者113例。按照气管镜检查时出血量的多少分为出血组和对照组。出血组定义为出血量＞100 ml，其中出血量＞300 ml定义为大出血；对照组为出血量＜100 ml。记录患者的各种临床指标、活检情况与病理诊断结果。结果两组年龄和乙肝、丙肝病毒感染阳性率差异有统计学意义(P＜0.05)，余指标差异无统计学意义(P＞0.05)。但是出血量＞300 ml的大出血组，曲霉菌感染和血管瘤是导致大出血的最危险病因。结论应警惕非恶性肿瘤患者活检时出血，尤其是曲霉菌感染和血管瘤。要严格气管镜的活检指征，降低大出血的发生率。
목적：분석기관경개입상관진료병발대출혈적위험인소。방법선택2011년12월-2012년12월해방군총의원호흡과개입폐장병중심경기관경진치적환자113례。안조기관경검사시출혈량적다소분위출혈조화대조조。출혈조정의위출혈량＞100 ml，기중출혈량＞300 ml정의위대출혈；대조조위출혈량＜100 ml。기록환자적각충림상지표、활검정황여병리진단결과。결과량조년령화을간、병간병독감염양성솔차이유통계학의의(P＜0.05)，여지표차이무통계학의의(P＞0.05)。단시출혈량＞300 ml적대출혈조，곡매균감염화혈관류시도치대출혈적최위험병인。결론응경척비악성종류환자활검시출혈，우기시곡매균감염화혈관류。요엄격기관경적활검지정，강저대출혈적발생솔。
Objective To analyze the risk factors for massive hemorrhage in bronchoscopy. Methods One hundred and thirteen patients who underwent bronchoscopy in our hospital from December 2011 to December 2012 were divided into hemorrhage group (blood loss>100 ml) and control group (blood loss<100 ml). Blood loss>300 ml was considered as massive hemorrhage. Their clinical indicators, biopsyfindings, and pathological diagnosis were recorded.Results The age and positive rate of hepatitis B or C virus infection were significantly different between the two groups (P<0.05); while no significant difference found in the other indications (P>0.05).Aspergillus infection and hemangioma were the most significant risk factors for massive hemorrhage when the blood loss was>300 ml.Conclusion Hemorrhage should be seriously considered in biopsy of non-malignant tumor patients especially withAspergillus infection and hemangioma. Strict control of biopsy indications for bronchoscopy can reduce the occurrence of massive hemorrhage.