CAJ | 학술논문

目的：探讨纳洛酮治疗脑血栓的临床应用和疗效。方法：选取我院在2010年～2012年收治的脑血栓患者80例，将所有患者随机分为观察组和对照组，对照组给予常规治疗，观察组在常规治疗的基础上加用盐酸纳洛酮治疗，对2组的治疗效果进行比较。结果：（1）2组疗效的比较，观察组总有效率（92．5％）明显大于对照组（77．5％），且P＜0．05；（2）对2组患者神经功能缺损情况的比较，治疗前2组无明显差异P＞0．05，治疗后，观察组神经功能缺损改善情况明显优于对照组，且P＜0．05。结论：在常规治疗的基础上，加用纳洛酮治疗脑血栓患者疗效确切，可明显改善患者的临床症状，值得推广。
목적：탐토납락동치료뇌혈전적림상응용화료효。방법：선취아원재2010년～2012년수치적뇌혈전환자80례，장소유환자수궤분위관찰조화대조조，대조조급여상규치료，관찰조재상규치료적기출상가용염산납락동치료，대2조적치료효과진행비교。결과：（1）2조료효적비교，관찰조총유효솔（92．5％）명현대우대조조（77．5％），차P＜0．05；（2）대2조환자신경공능결손정황적비교，치료전2조무명현차이P＞0．05，치료후，관찰조신경공능결손개선정황명현우우대조조，차P＜0．05。결론：재상규치료적기출상，가용납락동치료뇌혈전환자료효학절，가명현개선환자적림상증상，치득추엄。
Objective:To investigate the clinical application and effect of naloxone for treatment of cerebral thrombosis .Methods:We selected 80 patients with cerebral thrombosis treated in our hospital from 2010 to 2012 .All patients were randomly divided into observation group and control group .The control group was given conventional treatment , while the observation group was added naloxone hydrochlo-ride to conventional treatment .The effect of treatment in the two groups was compared .Results:Firstly, the clinical effect of the two groups was compared.The total effective rate of observation group (92.5%)was obviously higher than control group (77.5%), and there was an significant difference between the two groups (P<0.05);Secondly, neurologic deficits of patients in the two groups were com-pared.There was no difference between the two groups before treatment (P>0.05).But after treatment, the improvement of neurologic deficits of the observation group was obviously better than control group (P<0.05).Conclusion:The use of naloxone on the base of con-ventional therapy in the treatment of cerebral thrombosis had an accurate efficacy , and it significantly improves the patients'clinical symp-toms.It should be worthy of promotion .