CAJ | 학술논문

目的：探讨肺气肿多层螺旋CT （MSCT）形态学与肺功能（PFT）指标的相关性．方法随机选取33例有慢性阻塞性肺疾病（COPD）临床表现者，1周内完成CT和PFT检查．MSCT深吸气末扫描全肺，后处理工作站中定量测定肺密度、肺径线、肺容积共12项形态学指标，并与肺功能指标行相关性分析．结果 FEV1.0%与右上肺密度（＝0.391，＝0.048）、右下肺密度（＝0.465，＝0.038）、平均肺密度（＝0.576，＝0.025）、全肺容积（＝0.471，＝0.043）、右上肺容积（＝0.413，＝0.049）；FEV1.0/FVC与左下肺密度（＝0.392，＝0.024）、平均肺密度（＝0.703，＝0.000）、全肺横径（＝0.521，＝0.02）、右上肺最大横径（＝0.627，＝0.001）、全肺容积（＝0.549，＝0.01）具有相关性；FVC与右上肺最大横径（＝0.378，＝0.032）、右肺最大横径（＝0.349，＝0.037）；TLC与平均肺密度（＝0.523，＝0.032）、右上肺最大横径（＝0.454，＝0.045）、全肺容积（＝0.628，＝0.001）、右肺容积（＝0.492，＝0.035）具有相关性．结论 MSCT肺形态学定量指标在诊断、评估肺气肿患者中具有良好的临床应用价值．
목적：탐토폐기종다층라선CT （MSCT）형태학여폐공능（PFT）지표적상관성．방법수궤선취33례유만성조새성폐질병（COPD）림상표현자，1주내완성CT화PFT검사．MSCT심흡기말소묘전폐，후처리공작참중정량측정폐밀도、폐경선、폐용적공12항형태학지표，병여폐공능지표행상관성분석．결과 FEV1.0%여우상폐밀도（＝0.391，＝0.048）、우하폐밀도（＝0.465，＝0.038）、평균폐밀도（＝0.576，＝0.025）、전폐용적（＝0.471，＝0.043）、우상폐용적（＝0.413，＝0.049）；FEV1.0/FVC여좌하폐밀도（＝0.392，＝0.024）、평균폐밀도（＝0.703，＝0.000）、전폐횡경（＝0.521，＝0.02）、우상폐최대횡경（＝0.627，＝0.001）、전폐용적（＝0.549，＝0.01）구유상관성；FVC여우상폐최대횡경（＝0.378，＝0.032）、우폐최대횡경（＝0.349，＝0.037）；TLC여평균폐밀도（＝0.523，＝0.032）、우상폐최대횡경（＝0.454，＝0.045）、전폐용적（＝0.628，＝0.001）、우폐용적（＝0.492，＝0.035）구유상관성．결론 MSCT폐형태학정량지표재진단、평고폐기종환자중구유량호적림상응용개치．
Objective To discuss the correlation between MSCT morphological index of emphysema and pulmonary function test (PFT) indexes. Methods We randomly selected 33 cases with chronic obstructive pulmonary disease (COPD),and conducted CT and PFT in a week. The whole lung was scanned by MSCT at the end of deep aspiration,and the post-processing workstation was used for quantitative determination of a total of 12 morphological indexes,including the density of lung, pulmonary diameter line,lung volume,and etc,then their correlation with lung function index was analyzed.Results FEV1.0%had correlation with upper right lung density ( =0.391, =0.391), lower right lung density ( =0.465, =0.038),the mean lung density ( =0.576,=0.576), and total lung capacity (=0.471, =0.471),upper right lung volume ( =0.413, =0.049) . FEV1.0/FVC had correlation with left lower lung density ( =0.392, =0.024), the mean lung density ( =0.703, = 0.000), total lung transverse diameter ( = 0.521, = 0.521), upper right lung maximum transverse diameter ( =0.627, =0.627), and total lung capacity ( =0.549, =0.549) correlation. FVC had correlation with upper right lung maximum transverse diameter ( = 0.378, = 0.378), characterized by maximum transverse diameter (=0.349, =0.037) . TLC had correlation with mean lung density (=0.523,=0.523), upper right lung maximum transverse diameter ( =0.454, =0.454), and total lung capacity (= 0.001), the right lung volume ( = 0.492, = 0.492) . Conclusion MSCT lung morphology quantitative indicators have good clinical application value in the diagnosis and assessment of emphysema patients.