昆明医科大学学报
昆明醫科大學學報
곤명의과대학학보
Journal of Kunming Medical University
2013年
12期
87-89,95
,共4页
帕瑞昔布%布托啡诺%曲马多%全身麻醉%苏醒期躁动
帕瑞昔佈%佈託啡諾%麯馬多%全身痳醉%囌醒期躁動
파서석포%포탁배낙%곡마다%전신마취%소성기조동
Parecoxib%Butorphanol%Tramadol%General anesthesia%Emergence agitation
目的：探讨不同麻醉药物对全麻苏醒期躁动（EA）的影响．方法将134例术后出现EA的患者随机分为A组（42例）、B组（45例）和C组（47例），术后分别采用帕瑞昔布40 mg、布托啡诺20μg/kg和曲马多1 mg/kg，静脉注射．比较各组治疗后躁动的改善程度、VAS评分及Ramsay镇静评分等．结果治疗后，A组、B组患者EA的程度显著低于C组（＜0.05）；治疗后，3组VAS评分显著下降，Ramsay镇静评分显著升高（＜0.05），其中C组VAS评分显著高于A组、B组，B组Ramsay镇静评分显著高于A组、C组（＜0.05）；治疗后，B组患者苏醒时间、PACU停留时间显著高于A组、C组（＜0.05）．结论帕瑞昔布治疗EA安全有效，可有效改善全身麻醉后EA患者的躁动程度，提高术后的镇静效果，缩短PACU停留时间．
目的：探討不同痳醉藥物對全痳囌醒期躁動（EA）的影響．方法將134例術後齣現EA的患者隨機分為A組（42例）、B組（45例）和C組（47例），術後分彆採用帕瑞昔佈40 mg、佈託啡諾20μg/kg和麯馬多1 mg/kg，靜脈註射．比較各組治療後躁動的改善程度、VAS評分及Ramsay鎮靜評分等．結果治療後，A組、B組患者EA的程度顯著低于C組（＜0.05）；治療後，3組VAS評分顯著下降，Ramsay鎮靜評分顯著升高（＜0.05），其中C組VAS評分顯著高于A組、B組，B組Ramsay鎮靜評分顯著高于A組、C組（＜0.05）；治療後，B組患者囌醒時間、PACU停留時間顯著高于A組、C組（＜0.05）．結論帕瑞昔佈治療EA安全有效，可有效改善全身痳醉後EA患者的躁動程度，提高術後的鎮靜效果，縮短PACU停留時間．
목적：탐토불동마취약물대전마소성기조동（EA）적영향．방법장134례술후출현EA적환자수궤분위A조（42례）、B조（45례）화C조（47례），술후분별채용파서석포40 mg、포탁배낙20μg/kg화곡마다1 mg/kg，정맥주사．비교각조치료후조동적개선정도、VAS평분급Ramsay진정평분등．결과치료후，A조、B조환자EA적정도현저저우C조（＜0.05）；치료후，3조VAS평분현저하강，Ramsay진정평분현저승고（＜0.05），기중C조VAS평분현저고우A조、B조，B조Ramsay진정평분현저고우A조、C조（＜0.05）；치료후，B조환자소성시간、PACU정류시간현저고우A조、C조（＜0.05）．결론파서석포치료EA안전유효，가유효개선전신마취후EA환자적조동정도，제고술후적진정효과，축단PACU정류시간．
Objective To explore the influence of different anesthetics on emergence agitation (EA) after general anesthesia. Methods 134 EA patients after general anesthesia were randomly divided into three groups. Group A (n=42), Group B (n=45) and Group C (n=47) was given intravenously parecoxib 40 mg, butorphanol 20μg/kg and tramadol 1 mg/kg, respectively. The improvement of agitation, VAS score and Ramsay score were compared and analyzed among the groups. Results After treatment, the degree of EA in Group A, Group B was significantly lower than that in Group C ( <0.05) . VAS score in all the cases was reduced, and Ramsay score was increased compared with that before treatment ( <0.05) . VAS score in Group C was significantly higher than that in Group A, Group B (<0.05) . Ramsay score in Group B was significantly higher than that in Group A, Group C (<0.05) . After treatment, awaking time and postanesthesia care unit (PACU) stay in Group B was significantly higher than that in Group A, Group C (<0.05) .Conclusions Parecoxib is safe and effective for EA after general anesthesia, it can effectively improve the degree of EA, increase postoperative sedative effect, and shorten PACU stay.
