CAJ | 학술논문

目的：分析铜绿假单胞菌( PA)临床分离株的耐药性，为PA感染的临床治疗提供依据。方法：回顾性调查某医院2012年1~12月PA感染情况，对分离出的448株PAE药敏试验结果进行统计分析。结果：448株铜绿假单胞菌对药物敏感率依次为头孢哌酮/舒巴坦、氨苄西林/舒巴坦100%，环丙沙星76%，头孢吡肟72.8%，哌拉西林/他唑巴坦69.4%，阿米卡星66.3%，头孢他啶65.6%，美罗培南64.8%，亚胺培南59.9%，米诺环素28.9%，复方磺胺甲噁唑2.4%和头孢呋辛0%。结论：PA是医院感染的主要病原菌之一，应对其加强耐药性监测，规范抗菌药物的应用，为临床合理应用抗菌药物提供参考。
목적：분석동록가단포균( PA)림상분리주적내약성，위PA감염적림상치료제공의거。방법：회고성조사모의원2012년1~12월PA감염정황，대분리출적448주PAE약민시험결과진행통계분석。결과：448주동록가단포균대약물민감솔의차위두포고동/서파탄、안변서림/서파탄100%，배병사성76%，두포필우72.8%，고랍서림/타서파탄69.4%，아미잡성66.3%，두포타정65.6%，미라배남64.8%，아알배남59.9%，미낙배소28.9%，복방광알갑오서2.4%화두포부신0%。결론：PA시의원감염적주요병원균지일，응대기가강내약성감측，규범항균약물적응용，위림상합리응용항균약물제공삼고。
Objective:To analyze the drug resistance of Pseudomonas aeruginosa( PA) isolated from clinical specimen to provide the guidance for the clinical treatment. Methods:The infection status of PA from January 2012 to December 2012 was reviewed retro-spectively, and the results of susceptibility test for 448 PA strains were analyzed. Results:The antibiotic susceptibility of the PA strains to cefoperazone sodium and sulbac, ampicillin aodium and aulbacta,aiprofloxacin,cefepime,piperacillin/ sulbactam,amikacin, ceftazi-dime,meropenem, imipenem, minocycline, selectrin and aefuroxime was 100%, 76%, 72. 8%, 69. 4%, 66. 3%, 65. 6%, 64. 8%, 59. 9%,28. 9%,2. 4% and 0%,respectively. Conclusion:PA is one of the main pathogenic bacteria for nosocomial infection. It is necessary to strengthen the drug resistance test and standardize the application of antibiotics in order to provide the reference for clinical rational use of antibacterial drugs.