中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
5期
773-775
,共3页
王春艳%杨建春%李云霞%马春文
王春豔%楊建春%李雲霞%馬春文
왕춘염%양건춘%리운하%마춘문
复方参芪软胶囊%正交试验%醇沉工艺%总多糖%干膏得率
複方參芪軟膠囊%正交試驗%醇沉工藝%總多糖%榦膏得率
복방삼기연효낭%정교시험%순침공예%총다당%간고득솔
Fufang Shenqi soft capsules%Orthogonal design%Ethanol precipitation technique%Total polysaccharides%Dry extract yielding rate
目的：优选复方参芪软胶囊的醇沉工艺。方法：采用正交试验设计,以药液中总多糖的含量和干膏得率为指标,考察浓缩液的相对密度、醇沉浓度、静置时间、醇沉温度对醇沉效果的影响。结果：最佳醇沉工艺为药液浓缩至相对密度1.10,加95%乙醇至含醇量为60%,室温下静置48 h。结论：优选的复方参芪软胶囊醇沉工艺简便易行,适用于实际生产配制。
目的：優選複方參芪軟膠囊的醇沉工藝。方法：採用正交試驗設計,以藥液中總多糖的含量和榦膏得率為指標,攷察濃縮液的相對密度、醇沉濃度、靜置時間、醇沉溫度對醇沉效果的影響。結果：最佳醇沉工藝為藥液濃縮至相對密度1.10,加95%乙醇至含醇量為60%,室溫下靜置48 h。結論：優選的複方參芪軟膠囊醇沉工藝簡便易行,適用于實際生產配製。
목적：우선복방삼기연효낭적순침공예。방법：채용정교시험설계,이약액중총다당적함량화간고득솔위지표,고찰농축액적상대밀도、순침농도、정치시간、순침온도대순침효과적영향。결과：최가순침공예위약액농축지상대밀도1.10,가95%을순지함순량위60%,실온하정치48 h。결론：우선적복방삼기연효낭순침공예간편역행,괄용우실제생산배제。
Objective:To optimize the ethanol precipitation technique for Fufang Shenqi soft capsules. Methods: An orthogonal design was used to optimize the technique with the relative density of the concentrated solution, ethanol concentration, standing time, temperature of ethanol precipitation as the influencing factors and the yield of dry extract and the content of total polysaccharides as the indices. Results:The best ethanol precipitation technique was as follows:the relative density of the concentrated solution was 1. 10, 95% ethanol was used to obtain 60% ethanol concentration, and the standing time was 48 h under the temperature of 10-30℃. Con-clusion:The optimized ethanol precipitation technique for Fufang Shenqi soft capsules is simple and practicable, and suitable for prac-tical production.
