国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
4期
588-591
,共4页
宫颈癌浸润癌%宫颈上皮内瘤变%人乳头瘤病毒%高危因素
宮頸癌浸潤癌%宮頸上皮內瘤變%人乳頭瘤病毒%高危因素
궁경암침윤암%궁경상피내류변%인유두류병독%고위인소
Invasive carcinoma of cervix%Cervical intraepithelial neoplasia%Human papillomavirus%High risk factors
目的 了解流动人口密集地区宫颈上皮内瘤变与高危型人乳头瘤病毒间的关系及相关因素.方法 对妇科门诊所有感染HPV16、HPV18、HPV31亚型患者的基本资料进行初步登记,再通过查阅电子病历或电话回访逐一完善相关资料.结果 从198例高危HPV感染患者中检出的217频次的阳性结果中发现:HPV16感染比率最多,占61.75％,HPV18其次,占25.35％,HPV31位居第三,占12.90％.198例患者中过早或多伴侣性生活的占16.16％,多孕、多产和多次人流占32.83％、感染性阴道炎占90.40％、慢性宫颈炎占81.82％；在198例高危HPV感染者中共发现了宫颈上皮内瘤变及宫颈浸润癌26例,26例宫颈上皮内瘤变及宫颈浸润癌患者中22例感染HPV16,其恶性程度也更高.结论 流动人口密集地区宫颈上皮内瘤变与高危型HPV16感染密切相关,慢性宫颈炎及阴道感染所致宫颈低免疫力是最主要的高危HPV感染因素.
目的 瞭解流動人口密集地區宮頸上皮內瘤變與高危型人乳頭瘤病毒間的關繫及相關因素.方法 對婦科門診所有感染HPV16、HPV18、HPV31亞型患者的基本資料進行初步登記,再通過查閱電子病歷或電話迴訪逐一完善相關資料.結果 從198例高危HPV感染患者中檢齣的217頻次的暘性結果中髮現:HPV16感染比率最多,佔61.75％,HPV18其次,佔25.35％,HPV31位居第三,佔12.90％.198例患者中過早或多伴侶性生活的佔16.16％,多孕、多產和多次人流佔32.83％、感染性陰道炎佔90.40％、慢性宮頸炎佔81.82％；在198例高危HPV感染者中共髮現瞭宮頸上皮內瘤變及宮頸浸潤癌26例,26例宮頸上皮內瘤變及宮頸浸潤癌患者中22例感染HPV16,其噁性程度也更高.結論 流動人口密集地區宮頸上皮內瘤變與高危型HPV16感染密切相關,慢性宮頸炎及陰道感染所緻宮頸低免疫力是最主要的高危HPV感染因素.
목적 료해류동인구밀집지구궁경상피내류변여고위형인유두류병독간적관계급상관인소.방법 대부과문진소유감염HPV16、HPV18、HPV31아형환자적기본자료진행초보등기,재통과사열전자병력혹전화회방축일완선상관자료.결과 종198례고위HPV감염환자중검출적217빈차적양성결과중발현:HPV16감염비솔최다,점61.75％,HPV18기차,점25.35％,HPV31위거제삼,점12.90％.198례환자중과조혹다반려성생활적점16.16％,다잉、다산화다차인류점32.83％、감염성음도염점90.40％、만성궁경염점81.82％；재198례고위HPV감염자중공발현료궁경상피내류변급궁경침윤암26례,26례궁경상피내류변급궁경침윤암환자중22례감염HPV16,기악성정도야경고.결론 류동인구밀집지구궁경상피내류변여고위형HPV16감염밀절상관,만성궁경염급음도감염소치궁경저면역력시최주요적고위HPV감염인소.
Objective To investigate the relevant factors and relationship between cervical intraepithelial neoplasia and high-risk human papillomavirus happened in the areas with dense floating population.Methods The basic data of the patients infected by HPV16,HPV18,and HPV31 subgroups from the gynecological clinic were collected,and the relevant data were completed reviewing their electronic medical records or through telephone follow-up.Results The HPV infection frequency was 217 in the 198 patients.Among them,61.75％ were infected by HPV16,25.35％ by HPV18,and 12.90％ by HPV31.In the 198 patients,16.16％ had sex life in too young age or had more than one sex mate,32.83％ had been pregnant,delivered,or aborted more than once,90.40％ got vaginal infection,81.82％ had chronic cervicitis,and 26 patients (13.13％),including 22 cases infected by HPV16 and having higher malignancy degree,had cervical intraepithelial neoplasia and cervical carcinoma.Conclusions Cervical intraepithelial neoplasia closely relates to high-risk HPV16 infection in the areas with dense floating population.Low immunity caused by chronic cervicitis and cervical and vaginal infections,was the main factors for high risk HPV infection.
