CAJ | 학술논문

目的：探讨320排CT首过灌注成像鉴别良恶性肺结节的临床实用性。方法灌注成功并明确诊断的肺结节51例，包括12例肺炎性结节，5例肺良性结节，34例肺恶性结节，所有病例均进行320排CT肺部动态容积扫描，利用灌注软件获取肺结节兴趣区的灌注参数值，并进行统计学分析。结果通过肺结节灌注参数伪彩图获取病灶实质部分的肺动脉灌注量(PAP)、支气管动脉灌注量(BAP)、肺动脉灌注指数(PAPI)等参数值，肺炎性结节、肺良性结节、肺恶性结节三组的各项灌注参数均有显著性差异。结论320排CT首过灌注成像对良恶性肺结节的鉴别诊断有优势，具有临床实用性和优越性。
목적：탐토320배CT수과관주성상감별량악성폐결절적림상실용성。방법관주성공병명학진단적폐결절51례，포괄12례폐염성결절，5례폐량성결절，34례폐악성결절，소유병례균진행320배CT폐부동태용적소묘，이용관주연건획취폐결절흥취구적관주삼수치，병진행통계학분석。결과통과폐결절관주삼수위채도획취병조실질부분적폐동맥관주량(PAP)、지기관동맥관주량(BAP)、폐동맥관주지수(PAPI)등삼수치，폐염성결절、폐량성결절、폐악성결절삼조적각항관주삼수균유현저성차이。결론320배CT수과관주성상대량악성폐결절적감별진단유우세，구유림상실용성화우월성。
Objective To explore the clinical application of 320-slice CT first-passperfusion imaging (CT-PWI) in differentiating benign and malignant pulmonary nodules. Methods 51 patients were diagnosed as pulmonary nodules,including inflammation (n=12), benign (n=5) and malignant(n=34)nodules. All the cases were performed thoracic dynamic volume CT examinations by 320-slice CT scanner. Perfusion parameters were acquired by perfusion software, and were statistically analyzed. Results Perfusion parameters such as pulmonary artery perfusion(PAP), bronchial artery perfusion(BAP), pulmonary artery perfusion index(PAPI) were acquired through pseudocolor maps. There were significant differences in the perfusion parameters among inflammatory, benign and malignant nodules. Conclusion Using 320-slice CT first-pass perfusion imaging(CT-PWI), it has advantages in differentiating benign and malignant pulmonary nodules, which possess practicability and superiority in clinic.