CAJ | 학술논문

目的：：探讨苯巴比妥高血浓度长期治疗急性脑炎伴癫痫患者的安全性。方法：选择我院2010年6月至2012年6月期间收治的急性脑炎伴癫痫患者共4例进行研究,静脉推注或肌内注射苯巴比妥。观察患者的各项体征变化,以及是否出现癫痫等情况。结果：苯巴比妥维持高血浓度期间,4例患者均处于昏迷状态,但脑电图监测未见爆发-抑制模式。结论：苯巴比妥高血浓度长期治疗可能会引发较严重的不良反应,因此高血浓度长期治疗期间必须对患者进行辅助呼吸,并密切进行观测,及时处理出现的各种不良反应。
목적：：탐토분파비타고혈농도장기치료급성뇌염반전간환자적안전성。방법：선택아원2010년6월지2012년6월기간수치적급성뇌염반전간환자공4례진행연구,정맥추주혹기내주사분파비타。관찰환자적각항체정변화,이급시부출현전간등정황。결과：분파비타유지고혈농도기간,4례환자균처우혼미상태,단뇌전도감측미견폭발-억제모식。결론：분파비타고혈농도장기치료가능회인발교엄중적불량반응,인차고혈농도장기치료기간필수대환자진행보조호흡,병밀절진행관측,급시처리출현적각충불량반응。
Objective:To explore the safety of phenobarbital high blood concentration of long-termtreatment of acute encephalitis with epilepsy.Methods:4 cases of acute encephalitis with epilepsy patients in our hospital from June 2010 to June 2012 were selected , and treated all of the patients with intravenous or intramuscular injection of phenobarbital.Observed all the signs of change,and the presence of conditions such as epilepsy of the patients.Results:During the maintenance of high blood concentration of phenobarbital, 4 cases of patients were in a coma, but EEG burst suppression pattern was not founded.Conclusion:Phenobarbital high blood concentration of long-term treatment may cause more severe adverse reactions,so the high blood concentration during long-term treatment must be assisted breathing on patients, and close observation, timely processing of all adverse events.