CAJ | 학술논문

目的：探讨组织多普勒成像评价急性冠状动脉综合征（ ACS）近期预后的价值。方法随机入选79例ACS患者，包括预后良好组（n＝58）和预后不良组（n＝21）。用超声组织多普勒成像（TDI）检查二尖瓣口舒张早期血流速度峰值（ E）与左心室侧壁二尖瓣环舒张早期运动速度（ Em）的比值（ E/Em）。研究预后不良的ACS患者E/Em的变化。用Pearson相关性分析ACS患者E/Em与血清肌钙蛋白肌钙蛋白I（ CTnI）水平的关系。用Logistic回归研究E/Em与血清CTnI异常是否是ACS近期预后不良的独立预测因子。结果与预后良好组比较，预后不良组ACS患者E/Em升高（分别为7．87±1．64、14．26±3．12，P＜0．05）。 ACS患者E/Em与血清CTnI水平呈正相关，r＝0．782，P＝0．000。E/Em上调是ACS近期预后不良的独立预测因子（OR＝3．12，P＝0．041）。结论 E/Em升高是ACS近期预后不良的独立预测因子。
목적：탐토조직다보륵성상평개급성관상동맥종합정（ ACS）근기예후적개치。방법수궤입선79례ACS환자，포괄예후량호조（n＝58）화예후불량조（n＝21）。용초성조직다보륵성상（TDI）검사이첨판구서장조기혈류속도봉치（ E）여좌심실측벽이첨판배서장조기운동속도（ Em）적비치（ E/Em）。연구예후불량적ACS환자E/Em적변화。용Pearson상관성분석ACS환자E/Em여혈청기개단백기개단백I（ CTnI）수평적관계。용Logistic회귀연구E/Em여혈청CTnI이상시부시ACS근기예후불량적독립예측인자。결과여예후량호조비교，예후불량조ACS환자E/Em승고（분별위7．87±1．64、14．26±3．12，P＜0．05）。 ACS환자E/Em여혈청CTnI수평정정상관，r＝0．782，P＝0．000。E/Em상조시ACS근기예후불량적독립예측인자（OR＝3．12，P＝0．041）。결론 E/Em승고시ACS근기예후불량적독립예측인자。
Objective To investigate the the predictive value of short-term prognosis in ACS patients with tissue Doppler imaging.Methods 79 patients with acute coronary syndrome (ACS),divided into good prognosis group(n=58)and poor prognosis group (n=21),were radomly selected.The patients were detected the E/Em ratio of early diastolic mitral inflow peak velocity ( E ) to myocardial early diastolic velocities at the lateral mitral annulus ( Em) measured by tissue Doppler imaging .Relation of E/Em ratio and serum CTnIwere analized by using Pearson correlation .Whether abnormal E/Em ratio could be independent predictor of ACS with poor prognosis or not was analized by Logistic regression .Results Compared with good prognosis group , the E/Em ratio increased in poor prognosis group (7.87 ±1.64 vs 14.26 ±3.12,P<0.05).Pearson correla-tion analysis indicted that E/Em ratio was positively associated with the level of serum CTnIin ACS patients ( r=0.782,P=0.000).The upregulation of E/Em ratio was independent predictor of ACS with poor prognosis (OR=3.12,P =0.041).Conclusion The upregulation of E/Em ratio has predictive value for ACS with poor prognosis .