CAJ | 학술논문

目的：观察胸水糖类抗原125（CA125）水平对结核性胸腔积液的临床意义。方法将2008-01～2014-01该院确诊为结核性胸膜炎并行胸水CA125测定的30例患者作为观察组，将确诊为肺炎旁胸腔积液或自身免疫性疾病合并胸腔积液的30例患者作为对照组，比较两组患者胸水CA125水平检测结果。结果观察组胸水CA125＜68.6 U／ml 3例，68.6 U／ml≤CA125≤600 U／ml 17例，＞600 U／ml 10例；对照组胸水CA125＜68.6 U／ml 1例，68.6 U／ml≤CA125≤600 U／ml 28例，＞600 U／ml 1例。两组比较差异具有统计学意义（ P＜0.01）。结论胸水CA125水平测定对结核性胸腔积液的诊断有一定的临床意义。
목적：관찰흉수당류항원125（CA125）수평대결핵성흉강적액적림상의의。방법장2008-01～2014-01해원학진위결핵성흉막염병행흉수CA125측정적30례환자작위관찰조，장학진위폐염방흉강적액혹자신면역성질병합병흉강적액적30례환자작위대조조，비교량조환자흉수CA125수평검측결과。결과관찰조흉수CA125＜68.6 U／ml 3례，68.6 U／ml≤CA125≤600 U／ml 17례，＞600 U／ml 10례；대조조흉수CA125＜68.6 U／ml 1례，68.6 U／ml≤CA125≤600 U／ml 28례，＞600 U／ml 1례。량조비교차이구유통계학의의（ P＜0.01）。결론흉수CA125수평측정대결핵성흉강적액적진단유일정적림상의의。
Objective To investigate the diagnostic value of the measurement of CA 125 in pleural effusion for tuberculous pleural effusion .Methods Thirty confirmed tuberculous pleurisy patients who received the measure-ment CA125 of pleural effusion from January 2008 to January 2014 were pooled into observation group .The control group 30 patients were made up of patients with parapneumonic effusion or autoimmune disease patients with pleural effusion.Measurement of CA125 in all patients′pleural effusion was performed by immunochemical fluorescent assay . Intergroup statistics analysis had been carried on .Results The observation group showed CA 125<68.6 U/ml in 3 patients,68.6 U/ml≤CA125≤600 U/ml in 17,>600 U/ml in 10.The control group showed CA125<68.6 U/ml in one patient,68.6 U/ml≤CA125≤600 U/ml in 28,>600 U/ml in 1.There was statistically significance between two groups ( P<0.05 ) .Conclusion Compared with parapneumonic effusion and autoimmune-associated pleural effu-sion, concentrations of CA 125 in tuberculous pleural effusion have a tendency inclination of higher level .Further-more, the measurement of CA125 in pleural effusion appears to be beneficial for diagnosing tuberculous pleural effu -sion in non-malignant pleural effusion patients .