CAJ | 학술논문

目的：分析研究慢性疲劳综合征(CFS)与轻中度抑郁症、焦虑症患者疲劳特征及抑郁、焦虑症状的差异。方法运用疲劳量表-14(FS-14)、汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)对182例CFS及轻中度抑郁症、焦虑症患者进行测评及统计分析。结果三组患者在躯体疲劳程度、精神疲劳程度及疲劳总分各方面均无显著性差异(P>0.05)；CFS组患者可能有抑郁症状的患者为39例(62.9%)，伴有轻中度抑郁症状的患者为23例(37.1%)，未发现肯定没有抑郁症状的患者；CFS组患者可能有焦虑症状的46例(74.2%)，肯定有焦虑症状的16例(25.8%)，未发现肯定没有焦虑症状的患者；CFS组HAMD总分显著低于轻中度抑郁症组(P<0.001)，两组在焦虑/躯体化、阻滞两因子中有非常显著性差异(P<0.01)，在认识障碍、日夜变化、绝望感各因子中有显著性差异(P<0.05)。CFS组HAMA总分显著低于轻中度焦虑症组(P<0.001)，两组在精神性焦虑方面有非常显著性差异(P<0.01)，在躯体性焦虑各方有显著性差异(P<0.05)。结论 CFS与轻中度抑郁症、焦虑症三组患者在临床中均表现为“郁”与“疲”的同时存在，在临床症状的表现上存在着一定的“相互重叠”现象。
목적：분석연구만성피로종합정(CFS)여경중도억욱증、초필증환자피로특정급억욱、초필증상적차이。방법운용피로량표-14(FS-14)、한밀이돈억욱량표(HAMD)화한밀이돈초필량표(HAMA)대182례CFS급경중도억욱증、초필증환자진행측평급통계분석。결과삼조환자재구체피로정도、정신피로정도급피로총분각방면균무현저성차이(P>0.05)；CFS조환자가능유억욱증상적환자위39례(62.9%)，반유경중도억욱증상적환자위23례(37.1%)，미발현긍정몰유억욱증상적환자；CFS조환자가능유초필증상적46례(74.2%)，긍정유초필증상적16례(25.8%)，미발현긍정몰유초필증상적환자；CFS조HAMD총분현저저우경중도억욱증조(P<0.001)，량조재초필/구체화、조체량인자중유비상현저성차이(P<0.01)，재인식장애、일야변화、절망감각인자중유현저성차이(P<0.05)。CFS조HAMA총분현저저우경중도초필증조(P<0.001)，량조재정신성초필방면유비상현저성차이(P<0.01)，재구체성초필각방유현저성차이(P<0.05)。결론 CFS여경중도억욱증、초필증삼조환자재림상중균표현위“욱”여“피”적동시존재，재림상증상적표현상존재착일정적“상호중첩”현상。
Objective To observe the difference among the patients with chronic fatigue syndrome (CFS), mild-to-moderate depression or anxiety disorders in symptoms of fatigue, depression and anxiety. Methods Fatigue Scale-14 (FS-14), Hamilton Rating Scale for Depres-sion (HAMD) and Hamilton Rating Scale for Anxiety (HAMA) were used to evaluate 182 cases with CFS, mild-to-moderate depression or anxiety disorders. Results There was no significant difference in physical fatigue, mental fatigue and comprehensive fatigue among 3 groups (P>0.05). There were 39 (62.9%) CFS patients perhaps with depression symptoms and 23 (37.1%) patients with mild-to-moderate de-pression symptoms. There were 46 (74.2%) CFS patients perhaps with anxiety symptoms and 16 (25.8%) patients with mild-to-moderate anxiety symptoms. The score of HAMD was significant lower in the CFS group than in the mild-to-moderate depression disorder group (P<0.001). There were significant differences in the anxiety/somatization and hysteresis (P<0.01), as well as in cognitive disturbance, diurnal variation and hopelessness (P<0.05) between the CFS group and mild-to-moderate depression disorder group. The scores of HAMA was sig-nificant lower in the CFS group than in the mild-to-moderate anxiety disorder group (P<0.001). There was significant difference in men-tal-anxiety (P<0.01), as well as in body-anxiety (P<0.05) between the CFS group and the mild-to-moderate anxiety disorder group. Conclu-sion The symptoms of emotion disorders and fatigue symptoms were both presented in patients with CFS, mild-to-moderate depression and anxiety disorders. They share common clinical features.