实用药物与临床
實用藥物與臨床
실용약물여림상
PRACTICAL PHARMACY AND CLINICAL REMEDIES
2014年
6期
781-783
,共3页
地诺前列酮%缩宫素%足月妊娠引产
地諾前列酮%縮宮素%足月妊娠引產
지낙전렬동%축궁소%족월임신인산
Dinoprostone%Ooxytocin%Inducing term labor
目的：观察地诺前列酮用于足月妊娠引产的效果及安全性。方法选择2012年6月至2013年6月来我院住院分娩有引产指征的70例初孕妇为研究对象,根据用药不同将70例孕妇分为2组：治疗组采用地诺前列酮引产,对照组采用缩宫素引产,比较两组的引产效果。结果对照组有效率为61．11%,治疗组为91．18%,治疗组促宫颈成熟效果明显优于对照组(χ2=8．639,P=0．013)。治疗组引产前后宫颈评分提高分值(2．73±1．68)分,明显高于对照组(1．83±1．12)分(t=2．622,P=0．011)。治疗组用药至临床时间、用药至分娩时间及总产程时间分别为(13．24±7．25) h、(17．38±7．53) h、(12．54±6．23) h,对照组则为(26．18±12．54) h、(35．72±17．89) h、(16．53±7．24) h,前者明显短于后者,两组比较差异有统计学意义( t =5．321、5．644、2．476,P=0．000、0．000、0．016)。结论地诺前列酮引产效果明显优于缩宫素,并具有安全、方便的特点。
目的：觀察地諾前列酮用于足月妊娠引產的效果及安全性。方法選擇2012年6月至2013年6月來我院住院分娩有引產指徵的70例初孕婦為研究對象,根據用藥不同將70例孕婦分為2組：治療組採用地諾前列酮引產,對照組採用縮宮素引產,比較兩組的引產效果。結果對照組有效率為61．11%,治療組為91．18%,治療組促宮頸成熟效果明顯優于對照組(χ2=8．639,P=0．013)。治療組引產前後宮頸評分提高分值(2．73±1．68)分,明顯高于對照組(1．83±1．12)分(t=2．622,P=0．011)。治療組用藥至臨床時間、用藥至分娩時間及總產程時間分彆為(13．24±7．25) h、(17．38±7．53) h、(12．54±6．23) h,對照組則為(26．18±12．54) h、(35．72±17．89) h、(16．53±7．24) h,前者明顯短于後者,兩組比較差異有統計學意義( t =5．321、5．644、2．476,P=0．000、0．000、0．016)。結論地諾前列酮引產效果明顯優于縮宮素,併具有安全、方便的特點。
목적：관찰지낙전렬동용우족월임신인산적효과급안전성。방법선택2012년6월지2013년6월래아원주원분면유인산지정적70례초잉부위연구대상,근거용약불동장70례잉부분위2조：치료조채용지낙전렬동인산,대조조채용축궁소인산,비교량조적인산효과。결과대조조유효솔위61．11%,치료조위91．18%,치료조촉궁경성숙효과명현우우대조조(χ2=8．639,P=0．013)。치료조인산전후궁경평분제고분치(2．73±1．68)분,명현고우대조조(1．83±1．12)분(t=2．622,P=0．011)。치료조용약지림상시간、용약지분면시간급총산정시간분별위(13．24±7．25) h、(17．38±7．53) h、(12．54±6．23) h,대조조칙위(26．18±12．54) h、(35．72±17．89) h、(16．53±7．24) h,전자명현단우후자,량조비교차이유통계학의의( t =5．321、5．644、2．476,P=0．000、0．000、0．016)。결론지낙전렬동인산효과명현우우축궁소,병구유안전、방편적특점。
Objective To analyze the effects and safety of dinoprostone on inducing term labor. Methods 70 cases of first pregnant women with inducing indicators in our hospital from June 2012 to June 2013 were divided into treatment group used dinoprostone for induction and control group used oxytocin for inducation. The efficacy of the two groups were compared. Results The efficiency of control group was 61. 11%,the treatment group was 91. 18%,the effects of promoting cervical ripening in treatment group was significantly better than that of the control group (χ2 =8. 639,P=0. 013). The score before and after treatment of treatment group (2. 73 ± 1. 68 ) was significantly higher than that of control group(1. 83 ± 1. 12)(t=2. 622,P=0. 011). The medicine time of clinical,delivery and the whole process in treatment group were (13. 24 ± 7. 25) h,(17. 38 ± 7. 53 )h,(12. 54 ± 6. 23) h respecitvely,which of control group were (26. 18 ± 12. 54 )h,(35. 72 ± 17. 89) h,(16. 53 ± 7. 24) h respectively,there were significant differences between the two groups (t=5. 321,5. 644,2. 476,P=0. 000,0. 000,0. 016). Conclusion Dinoprostone has better od-inopoeia effect than oxytocin,it is safe and convenient.
