CAJ | 학술논문

COPD是一种以气道慢性炎症为特征之一的慢性呼吸系统疾病,气道炎性反应在COPD占有重要作用.炎性细胞因子是机体内最重要的一类细胞因子,多种炎性细胞因子参与气道炎症的病理生理机制,对肺组织和支气管产生损害,并发肺外效应.在COPD的自然病程中存在炎性细胞因子网络系统,调控COPD的气道炎症的发生发展.
COPD시일충이기도만성염증위특정지일적만성호흡계통질병,기도염성반응재COPD점유중요작용.염성세포인자시궤체내최중요적일류세포인자,다충염성세포인자삼여기도염증적병리생리궤제,대폐조직화지기관산생손해,병발폐외효응.재COPD적자연병정중존재염성세포인자망락계통,조공COPD적기도염증적발생발전.
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease that characterized by chronic airway inflammatory reaction,airway inflammation plays an important role in COPD.Inflammatory cytokines is one of the most important cytokines,there are many inflammatory cytokines in pathological and physiological mechanism of airway inflammation,caused damage to lung and bronchus,and extrapulmonary effects.There is a inflammatory cytokines network system in the natural course of COPD,and regulate the occurrence and development of airway inflammation in COPD.