中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
5期
785-788
,共4页
肖璜%林吉恒%陈万胜%马仕洪%胡昌勤
肖璜%林吉恆%陳萬勝%馬仕洪%鬍昌勤
초황%림길항%진만성%마사홍%호창근
氯霉素滴眼液%尼泊金乙酯%硼酸/硼砂%抑菌效力
氯黴素滴眼液%尼泊金乙酯%硼痠/硼砂%抑菌效力
록매소적안액%니박금을지%붕산/붕사%억균효력
Chloramphenicol eye drops%Ethylparaben%Boric acid and borax%Antimicrobial effect
目的:调研国产氯霉素滴眼液中尼泊金乙酯含量不同产品是否符合《中国药典》规定。方法:通过抑菌剂效力检查法测定含不同浓度尼泊金乙酯模拟产品的抑菌效力。结果:证明现行产品浓度尼泊金乙酯模拟产品的抑菌效力均符合药典规定。结论:现行产品中的尼泊金乙酯处方浓度偏高。而处方中作为辅料的硼酸/硼砂,除具有pH调节作用外,对抑菌效力也有贡献。
目的:調研國產氯黴素滴眼液中尼泊金乙酯含量不同產品是否符閤《中國藥典》規定。方法:通過抑菌劑效力檢查法測定含不同濃度尼泊金乙酯模擬產品的抑菌效力。結果:證明現行產品濃度尼泊金乙酯模擬產品的抑菌效力均符閤藥典規定。結論:現行產品中的尼泊金乙酯處方濃度偏高。而處方中作為輔料的硼痠/硼砂,除具有pH調節作用外,對抑菌效力也有貢獻。
목적:조연국산록매소적안액중니박금을지함량불동산품시부부합《중국약전》규정。방법:통과억균제효력검사법측정함불동농도니박금을지모의산품적억균효력。결과:증명현행산품농도니박금을지모의산품적억균효력균부합약전규정。결론:현행산품중적니박금을지처방농도편고。이처방중작위보료적붕산/붕사,제구유pH조절작용외,대억균효력야유공헌。
Objective: To study whether domestic chloramphenicol eye drops with different ethylparabenin content meet the re-quirements in Chinese Pharmacopoeia. Methods:Antimicrobial effect test was used to examine the antimicrobial effect of the different eye drops. Results:The antimicrobial effect of the eye drops was in compliance with the requirements in the pharmacopoeia. Conclu-sion:The ethylparabenin concentration in the eye drops is higher than necessary. Boric acid and borax not only can adjust pH, but also show antimicrobial effect.