CAJ | 학술논문

目的探讨采用超声心动图测定心肌作功指数(Tei指数)评价慢性心力衰竭(CHF)患者心功能状态的价值.方法回顾性分析CHF患者60例(心衰组),健康者30例(对照组),所有入选者进行超声检测Tei指数,并将该指数与同期血浆氨基末端脑钠肽前体(NT-ProBNP)水平及纽约心功能分级(NYHA)进行比较,并评价其诊断CHF的敏感性、特异性.结果 (1)Tei指数在心衰组明显大于对照组,当Tei指数≥0.45时,其诊断CHF的敏感性、特异性、阳性预测值、阴性预测值分别为85.6％、90.4％、89.8％及78.0％.(2)相关性分析表明Tei指数与Log NT-ProBNP水平呈明显正相关(r=0.84,P＜0.01).(3)NYHAⅡ、Ⅲ、Ⅳ级患者的Tei指数为(0.47±0.06)、(0.56±0.08)和(0.64±0.13),组间差异均有统计学意义(P＜0.05).结论应用Tei指数客观评价慢性心力衰竭严重程度是可行的.
목적 탐토채용초성심동도측정심기작공지수(Tei지수)평개만성심력쇠갈(CHF)환자심공능상태적개치.방법 회고성분석CHF환자60례(심쇠조),건강자30례(대조조),소유입선자진행초성검측Tei지수,병장해지수여동기혈장안기말단뇌납태전체(NT-ProBNP)수평급뉴약심공능분급(NYHA)진행비교,병평개기진단CHF적민감성、특이성.결과 (1)Tei지수재심쇠조명현대우대조조,당Tei지수≥0.45시,기진단CHF적민감성、특이성、양성예측치、음성예측치분별위85.6％、90.4％、89.8％급78.0％.(2)상관성분석표명Tei지수여Log NT-ProBNP수평정명현정상관(r=0.84,P＜0.01).(3)NYHAⅡ、Ⅲ、Ⅳ급환자적Tei지수위(0.47±0.06)、(0.56±0.08)화(0.64±0.13),조간차이균유통계학의의(P＜0.05).결론 응용Tei지수객관평개만성심력쇠갈엄중정도시가행적.
Objective To explor the value of Tei index for evaluation the cardiac function of patients with chronic heart failure(CHF).Methods Tei index in 60 patients with CHF(CHF group) and 30 normal controls(control group) were evaluated and compared with the levels of NT-ProBNP and the NYHA class,and the sensitivity and specificity of Tei index for CHF diagnosis were appraised.Results (1) Tei index in CHF group was significantly higher than that in control group.When Tei index was more than and equal to 0.45,the sensitivity,specificity,positive predictive value,and negative predictive value of Tei index for diagnosing CHF were 85.6％,90.4％,89.8％ and 78.0％.(2)There was a remarkable positive correlation between Tei and Log NT-ProBNP(r =0.84,P ＜ 0.01).(3)There were significant differences in Tei index among NYHA Ⅱ,Ⅲ,Ⅳ class [(0.47 ± 0.06),(0.56 ± 0.08),(0.64 ±0.13)].Conclusion Tei index can be used to diagnose CHF and evaluate the degree of it.