CAJ | 학술논문

目的：探讨小儿肺部不同细菌病原体感染时，人体降钙素原（ PCT）、C－反应蛋白（ CRP）的血清水平及白细胞（WBC）计数的变化。方法选取西安市儿童医院重症医学科肺部感染患者83例，分为革兰阴性菌组（49例）、革兰阳性菌组（34例）。入院后对患儿取晨起空腹静脉血5mL，行PCT、CRP测定，白细胞计数等检查。结果革兰阴性菌组PCT水平高于革兰阳性菌组，差异有统计学意义（t＝8．44，P＜0．05）；两组患儿的CRP水平差异无统计学意义（t＝1．61，P＞0．05）；两组患儿白细胞计数差异也无统计学意义（t＝0．36，P＞0．05）。结论降钙素原可用来区分肺部革兰阴性菌及革兰阳性菌感染，而CRP及白细胞计数特异性较低。
목적：탐토소인폐부불동세균병원체감염시，인체강개소원（ PCT）、C－반응단백（ CRP）적혈청수평급백세포（WBC）계수적변화。방법선취서안시인동의원중증의학과폐부감염환자83례，분위혁란음성균조（49례）、혁란양성균조（34례）。입원후대환인취신기공복정맥혈5mL，행PCT、CRP측정，백세포계수등검사。결과혁란음성균조PCT수평고우혁란양성균조，차이유통계학의의（t＝8．44，P＜0．05）；량조환인적CRP수평차이무통계학의의（t＝1．61，P＞0．05）；량조환인백세포계수차이야무통계학의의（t＝0．36，P＞0．05）。결론강개소원가용래구분폐부혁란음성균급혁란양성균감염，이CRP급백세포계수특이성교저。
Objective To detect the value of procalcitonin (PCT), C-reactive protein (CRP) and white blood cells (WBC) count in infant pulmonary bacterial infection with different pathogens .Methods A sample of 83 inpatients with pulmonary infection and hospitalized in pediatric intensive medicine of Xi ’ an Children ’ s Hospital were divided into gram-negative bacteria group ( 49 cases ) and gram-positive bacteria group (34 cases).After admission 5mL serum specimens were obtained to detect PCT , CRP and WBC count.Results The concentration of PCT in gram-negative bacteria group was significantly higher than gram-positive bacteria group (t=8.44, P<0.05). CRP and WBC count showed no significant difference between two groups (t value was 1.61 and 0.36, respectively, both P>0.05). Conclusion PCT can be used to distinguish gram-negative bacterium infection from gram-positive bacterium infection in infant pneumonia , and the specificity of CRP and WBC is low .