CAJ | 학술논문

精原干细胞（spermatogonial stem cells，SSCs）是各种雄性动物生殖细胞的母细胞，是一群具有自我更新和分化潜能的细胞，并且在雄性个体中精原干细胞与下一代的遗传背景密切相关。因此，精原干细胞在细胞生物学、医学、转基因等领域的研究有着广阔的应用前景。文章根据国内外相关研究进展，对精原干细胞的生物学特性、分离纯化与培养、移植等作一概述。
정원간세포（spermatogonial stem cells，SSCs）시각충웅성동물생식세포적모세포，시일군구유자아경신화분화잠능적세포，병차재웅성개체중정원간세포여하일대적유전배경밀절상관。인차，정원간세포재세포생물학、의학、전기인등영역적연구유착엄활적응용전경。문장근거국내외상관연구진전，대정원간세포적생물학특성、분리순화여배양、이식등작일개술。
Spermatogonial stem cells are oocytes of male mamals germ cells which not only can maintain the number of themselves but also can differentiate to spermatocyte. Spermatogonial stem cells are also closely related to the genetic background of the next male generation individuals. Therefore, the study of spermatogonial stem cells in the field of cell biology,medicine and transgene has broad application prospects. In this review,biological characteristics,isolation,purification,cultivation and transplantation of spermatogonial stem cells were discussed.