微生物学免疫学进展
微生物學免疫學進展
미생물학면역학진전
PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY
2014年
5期
48-51
,共4页
沈平%袁德媚%吴美旺%韦建立%黄志贵%沈佩玲
瀋平%袁德媚%吳美旺%韋建立%黃誌貴%瀋珮玲
침평%원덕미%오미왕%위건립%황지귀%침패령
乙型肝炎%白喉%疫苗%儿童%免疫效果%分析
乙型肝炎%白喉%疫苗%兒童%免疫效果%分析
을형간염%백후%역묘%인동%면역효과%분석
Hepatitis B%Diphtheria%Vaccine%Children%Immune effect%Analysis
目的：分析钦南区儿童乙肝及白喉疫苗接种后的免疫效果，为该地区儿童免疫规划工作提供科学依据。方法采用整群随机抽样方法，选取5个乡镇1～6岁常住儿童151名为调查对象，进行病毒性乙型肝炎（乙肝）、白喉血清学检测，并对结果进行分析。结果 HBsAg阳性2人，阳性率1．32％；抗-HBs阳性112人，阳性率74．17％。白喉IgG阳性142人，阳性率94．04％。抗-HBs中位数21．32 mIU/mL，白喉IgG中位数0．14 mIU/mL，乙肝疫苗首针及时接种率83．44％；男女抗-HBs阳性率、白喉IgG阳性率、抗体中位数差异均无统计学意义（ P＞0．05），抗-HBs阳性率、白喉IgG阳性率随年龄的增长而下降（P＜0．01）。结论钦南区1～6岁儿童乙肝疫苗接种率、首针及时接种率均达到了国家免疫规划的目标，白喉IgG阳性率维持较高的水平，但HBsAg阳性率略高于国家免疫规划的目标，儿童免疫规划工作仍需进一步加强。
目的：分析欽南區兒童乙肝及白喉疫苗接種後的免疫效果，為該地區兒童免疫規劃工作提供科學依據。方法採用整群隨機抽樣方法，選取5箇鄉鎮1～6歲常住兒童151名為調查對象，進行病毒性乙型肝炎（乙肝）、白喉血清學檢測，併對結果進行分析。結果 HBsAg暘性2人，暘性率1．32％；抗-HBs暘性112人，暘性率74．17％。白喉IgG暘性142人，暘性率94．04％。抗-HBs中位數21．32 mIU/mL，白喉IgG中位數0．14 mIU/mL，乙肝疫苗首針及時接種率83．44％；男女抗-HBs暘性率、白喉IgG暘性率、抗體中位數差異均無統計學意義（ P＞0．05），抗-HBs暘性率、白喉IgG暘性率隨年齡的增長而下降（P＜0．01）。結論欽南區1～6歲兒童乙肝疫苗接種率、首針及時接種率均達到瞭國傢免疫規劃的目標，白喉IgG暘性率維持較高的水平，但HBsAg暘性率略高于國傢免疫規劃的目標，兒童免疫規劃工作仍需進一步加彊。
목적：분석흠남구인동을간급백후역묘접충후적면역효과，위해지구인동면역규화공작제공과학의거。방법채용정군수궤추양방법，선취5개향진1～6세상주인동151명위조사대상，진행병독성을형간염（을간）、백후혈청학검측，병대결과진행분석。결과 HBsAg양성2인，양성솔1．32％；항-HBs양성112인，양성솔74．17％。백후IgG양성142인，양성솔94．04％。항-HBs중위수21．32 mIU/mL，백후IgG중위수0．14 mIU/mL，을간역묘수침급시접충솔83．44％；남녀항-HBs양성솔、백후IgG양성솔、항체중위수차이균무통계학의의（ P＞0．05），항-HBs양성솔、백후IgG양성솔수년령적증장이하강（P＜0．01）。결론흠남구1～6세인동을간역묘접충솔、수침급시접충솔균체도료국가면역규화적목표，백후IgG양성솔유지교고적수평，단HBsAg양성솔략고우국가면역규화적목표，인동면역규화공작잉수진일보가강。
Objective To analyse effect for children 1~6 years age immunized by hepatitis B and diphtheria vaccines in Qinnan district, Qinzhou city, and provide a scientific basis in children ’s immunization program.Methods A total of 151 children 1~6 years age were selected as investigation subject by using a random samplingtest , who permanently live in 5 townships,in serological detection and analysisof viral hepatitis B and diphtheria .Results The detected results showed , two samples are positive for HBsAg with a positive rate 1.32%, and 112 samples arepositive for anti-HBs with a positive rate 74.17%, 142 samples are positive for diphtheria IgG with a positive rate 94.04%;anti-HBs median is 21.32 mIU/mL, diphtheria IgG medianis 0.14 mIU/mL.The vaccination rate for first doseof HBV timely is 83.44%.There have no statistical differences (P>0.05) in positive rate for anti-HBs, for diphtheria IgG antibody,and anti-HBs medianand diph-theria IgG medianin both sexes ,respectively .The positive rate foranti-HBsand for diphtheria IgG increase with thegrowingof age(P<0.01).Conclusion It is complied with“Expanding national immunization planning implementation plan”in re-gard of rate for coverage and vaccination for first dose of hepatitis B vaccine to children 1~6 years age in Qinnan district . The positive rate for diphtheria IgG maintains in a high level , but positive rate for HBsAg is a little higher than that in the national plan .It should further strengthen implimentation of immunization program for children .
